
LMO2 - Wikipedia
LIM domain only 2 (rhombotin-like 1), also known as LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in …
Pathology Outlines - LMO2
2021年7月2日 · Vasculature is LMO2- in adult and fetal heart, brain of older adults, hepatic sinusoids, and hepatocellular carcinoma (Am J Clin Pathol 2009;131:264)
LMO2 Gene - GeneCards | RBTN2 Protein | RBTN2 Antibody
2024年12月25日 · LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic …
Structure of the leukemia oncogene LMO2: implications for the ...
2011年2月17日 · Through its LIM domains, LMO2 is thought to function as the scaffold for a DNA-binding transcription regulator complex, including the basic helix-loop-helix proteins SCL/TAL1 …
LMO2 expression is frequent in T-lymphoblastic leukemia and ...
LIM-domain only 2 (LMO2) is a critical regulator of hematopoietic cell development that can be overexpressed in T-LL due to chromosomal abnormalities. Deregulated LMO2 expression …
LMO2 at 25 years: a paradigm of chromosomal translocation ...
LMO2 was first discovered through proximity to frequently occurring chromosomal translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its role in tumours and …
A comprehensive analysis of LMO2 pathogenic regulatory ...
2022年7月18日 · LMO2 is a well-known leukemic proto-oncogene, its ectopic expression in T-lineage specifically initiates malignant transformation of immature T cells and ultimately …