2021年8月19日 · What is LL-37 Antimicrobial Peptide? LL-37 is a 37-amino-acid peptide that is directly derived from the C-terminal of a larger protein in your body known as a cathelicidin, …

LL-37 is able to kill bacteria through direct antibacterial activities, as well as through immunomodulation. Like other AMPs, the primary mechanism of action is membrane …

Cathelicidin antimicrobial peptide (CAMP) is an antimicrobial peptide encoded in the human by the CAMP gene. [1] . The active form is LL-37. In humans, CAMP encodes the peptide …

LL-37, expressed on the surface of neutrophils is recognized by anti-LL-37 autoantibodies, which promotes NETosis, generating a source of additional LL-37 DNA complexes. However, LL-37 …

LL-37 plays an important role in the first line of defense against infection and systemic invasion of pathogens at sites of inflammation and wound. It is cytotoxic to both bacterial and normal …

2024年3月8日 · In this review article, we aim to develop integrative, mechanistic insight into LL37 and its derived peptides, based on the known biophysical, structural, and functional studies in …

2020年8月4日 · LL-37 17–29 correspondingly forms wide, ribbon-like, thermostable fibrils in solution, which co-localize with bacterial cells. Structure-guided mutagenesis analyses …

LL-37, the only human cathelicidin-derived antimicrobial peptide, has long been a popular research subject because of its special abilities and vast applications. In the past 15 years, …

2025年1月1日 · Offering new strategies for treating chronic infections, LL-37 disrupts biofilms, particularly in antibiotic-resistant bacteria. Displaying both anti- and pro-cancerous effects, LL …

LL-37 (CAS number: 154947-66-7), also known as hCAP18, is the C-terminal part of the only human cathelicidin identified to date called human cationic antimicrobial protein (hCAP). LL-37 …