Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. [5] . It may be a metastasis suppressor. The leucine-rich glioma inactivated …

LGI1 (Leucine-rich glioma-inactivated 1) antibody encephalitis is an autoantibody mediated form of limbic encephalitis. It is the most common antibody-mediated encephalopathy in those over …

The LGI1 gene provides instructions for making a protein called leucine-rich glioma inactivated 1 (Lgi1) or epitempin. This protein is found primarily in nerve cells (neurons) in the brain, …

2020年4月14日 · LGI1 antibody encephalitis is characterized by encephalopathy and seizures (including hallmark faciobrachial dystonic seizures). Comparisons of immunotherapy and …

Leucine-rich, glioma inactivated 1 (LGI1) is a secreted glycoprotein, mainly expressed in the brain, and involved in central nervous system development and physiology. Mutations of LGI1 have …

2024年12月25日 · LGI1 (Leucine Rich Glioma Inactivated 1) is a Protein Coding gene. Diseases associated with LGI1 include Epilepsy, Familial Temporal Lobe, 1 and Autosomal Dominant …

The LGI1 gene encodes a secreted leucine-rich protein that is expressed in brain and plays a role in regulating postnatal glutamatergic synapse development (summary by Anderson, 2010).

LGI1, a secreted synaptic protein mutated to cause human partial epilepsy, regulates a seizure-induced circuit response by redistributing Kv4.2 channels to the neuronal surface in a …

This is the Epilepsiome page on LGI1, a gene for a familial focal epilepsy syndrome referred to a as autosomal dominant partial epilepsy with auditory features. LGI1 is one of the few genes for …

LGI1 appears to be a major actor of synaptic regulation by modulating trans-synaptically pre- and post-synaptic proteins. In this review, we will focus on LGI1 binding partners, "A Disintegrin …