2024年12月25日 · LEF1 (Lymphoid Enhancer Binding Factor 1) is a Protein Coding gene. Diseases associated with LEF1 include Split Hand-Foot Malformation and Ectrodactyly And …

2017年6月1日 · Lymphoid enhancer-binding factor 1 (LEF1), a member of the T-cell Factor (TCF)/LEF1 family of high-mobility group transcription factors, is a downstream mediator of the …

Recently, the role of lymphocyte enhancer-binding factor 1 (LEF1) in CLL was elucidated being highly expressed and seeming to have a prognostic value. Our aim was to test the applicability …

2021年10月6日 · Using high-throughput chromosome-conformation-capture sequencing, we demonstrate that Tcf1/Lef1 are important for maintaining three-dimensional genome …

2025年2月8日 · LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. The beta-catenin-LINC00183-miR-371b-5p-Smad2/LEF1 axis promotes …

Lymphoid enhancer-binding factor 1 (LEF1), a member of the T-cell Factor (TCF)/LEF1 family of high-mobility group transcription factors, is a downstream mediator of the Wnt/β-catenin …

LEF-1 is a DNA-binding protein in the control of transcription and has been shown to be central in organogenesis where there is bidirectional interaction of mesenchyme and epithelia.

2025年2月8日 · Data indicate Lef1 binds Pax3 & the complex binds to Lef1 promoter at Lef1 binding sites to enhance transcription of Lef1. In adult mouse brain, beta-catenin and LEF1 …

2023年7月20日 · We found that functional LEF1 and LEF1 regulon activity is reduced with age in multiple immune cell types from different human and murine tissues. We also showed that two …

Recently, the role of lymphocyte enhancer-binding factor 1 (LEF1) in CLL was elucidated being highly expressed and seeming to have a prognostic value. Our aim was to test the applicability …