2010年6月25日 · We used an oriented peptide library approach with five degenerate positions to probe the specificity of the major cNLS-binding site in importin-α. We identified the sequences …

The first NLS to be discovered was the sequence PKKKRKV in the SV40 Large T-antigen (a monopartite NLS). [2] . The NLS of nucleoplasmin, KR [PAATKKAGQA]KKKK, is the prototype …

2003年10月15日 · The nuclear import of simian-virus-40 large T-antigen (tumour antigen) is enhanced via phosphorylation by the protein kinase CK2 at Ser112 in the vicinity of the NLS …

2001年5月1日 · A peptide carrying the nuclear leader sequence of the simian virus SV40 large tumor antigen, KKKRK, was used to direct the fluorophore to the nucleus. The fluorescent …

2021年5月22日 · For example, the NLS of SV40 large T-antigen is 126 PKKKRKV 132, with five consecutive positively charged amino acids (KKKRK). Interestingly, studies have shown that …

A peptide carrying the nuclear leader sequence of the simian virus SV40 large tumor antigen, KKKRK, was used to direct the fluorophore to the nucleus. The fluorescent peptides for …

Question: Choose all that apply: The NLS (nuclear localization signal/ sequence) ... - has a consensus basic amino acid residue sequence, KKKRK. -is recognized by a nuclear import …

Access easy-to-understand explanations and practical examples on key biology topics, from cells to ecosystems. Learn at your own pace with bite-sized verified content. Which DNA base pair …

-has a consensus basic amino acid residue sequence, KKKRK. -is a short stretch of amino acyl residues in the protein destined to the nucleus. -is recognized by a soluble nuclear import …

2025年2月8日 · Study identified the sequences KKKRR, KKKRK, and KKRKK as the optimal sequences for binding to this site for mouse importin-alpha2, human importin-alpha1, and …