The Kell antigen system (also known as the Kell–Cellano system) is a human blood group system, that is, a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which …

The Kell blood group system is complex and contains many antigens that are highly immunogenic. These antigens are the third most potent, after those of the ABO and Rh blood groups, at triggering an immune reaction.

2024年10月28日 · The Kell blood group system is a collection of antigens found on red blood cells, erythroid cells, myeloid progenitor cells, and other tissues. These antigens are highly immunogenic, following only the ABO and Rhesus D systems in significance.

2024年9月11日 · Imprecisely called “Kell,” the K antigen is the most important antigen in the Kell system. Anti-K causes serious problems in transfusion and pregnancy.

Kell blood group system, classification of human blood based on the presence on the surfaces of red blood cells of various antigens encoded by the KEL gene. The system, discovered in 1946, is characterized by a high degree of polymorphism (genetic variation), and thus studies of …

The Kell blood group system contains more than 25 antigens and the main antigens are known as K (K1) and k (K2) and a variety of nucleotide mutations that cause single amino acid substitutions in the K protein give rise to the majority of the Kell antigens.

2024年2月27日 · The body's immune system may attack the Kell antigen system, a set of surface markers on red blood cells that aid in blood type determination and can result in illnesses that kill red blood cells. These antigens belong to a protein known as the Kell protein, which is crucial for cleaving endothelin-3.

2023年11月21日 · Learn the definition of the Kell antigen system, find its history and understand the Kell-negative and Kell-positive blood types. Updated: 11/21/2023. What Is the Kell Antigen System? What...

Anti-k (KEL2) antibodies react with the erythrocytes of more than 99% of the random population. Kell system antigens are present only in relatively low density on the erythrocyte membrane. The Duffy blood group system is comprised of human erythrocyte epitopes encoded by Fya and Fyb genes, located on chromosome 1. Mothers immunized through ...

The Kell antigen system (also known as Kell-Cellano system) is a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells.