KAT2A Gene - GeneCards | KAT2A Protein | KAT2A Antibody
2024年12月25日 · KAT2A (Lysine Acetyltransferase 2A) is a Protein Coding gene. Diseases associated with KAT2A include Chromosome 16P13.3 Deletion Syndrome, Proximal and …
KAT2A - Wikipedia
Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene. [5] [6]
KAT2A coupled with the α-KGDH complex acts as a histone H3
2017年12月6日 · Here we show that the α-ketoglutarate dehydrogenase (α-KGDH) complex is localized in the nucleus in human cell lines and binds to lysine acetyltransferase 2A (KAT2A, …
KAT2A lysine acetyltransferase 2A [ (human)] - National Center for ...
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting …
Histone acetyltransferase Kat2a regulates ferroptosis via …
2024年6月10日 · Our study revealed an upregulation of lysine acetyltransferase 2 A (Kat2a) expression in DCM, accompanied by a decrease in N6-methyladenosine (m6A) modified …
ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to …
2025年2月4日 · In this study, we demonstrated that activation of epidermal growth factor receptor (EGFR) induced translocation of acetyl-CoA synthetase 2 (ACSS2) into the nucleus, where …
KAT2A and KAT2B prevent double-stranded RNA accumulation …
2024年8月7日 · In this study, we find that double knockout (DKO) of lysine acetyltransferases 2A (Kat2a) and 2B (Kat2b) in the intestinal epithelium triggers an intrinsic IFN response and …
KAT2A complexes ATAC and SAGA play unique roles in cell …
We focus on KAT2A, a lysine acetyltransferase responsible for histone H3 lysine 9 acetylation, which we recently identified as a dependence in acute myeloid leukemia stem cells and that …
Targeting KAT2A inhibits inflammatory macrophage activation …
Our study proves that acetyltransferase KAT2A licenses metabolic and epigenetic reprogramming for NLRP3 inflammasome activation in inflammatory macrophages, thereby targeting KAT2A …
KAT2A lysine acetyltransferase 2A [ Homo sapiens (human) ]
2024年12月27日 · KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) …