KLF9 - Wikipedia
A Klf9 deficiency suppresses bleomycin-induced fibrosis in the lungs of mice. By introducing bleomycin to lung tissue, the tissue will produce ROS and develop fibrotic lung tissue to …
摘 要：KLF9是锌指蛋白Krüppel样转录因子(Krüppel-like factors, KLFs)家族的重要成员，通过C 端的3 个 C2H2 锌指蛋白结构，结合到靶基因启动子区富含GC 的区域，调节靶基因的转录，从 …
KLF9 Gene - GeneCards | KLF9 Protein | KLF9 Antibody
Dec 25, 2024 · KLF9 (KLF Transcription Factor 9) is a Protein Coding gene. Diseases associated with KLF9 include Familial Partial Lipodystrophy and Otosclerosis. Among its related pathways …
Klf9 is essential for cardiac mitochondrial homeostasis
Nov 8, 2024 · Here we show that cardiac Krüppel-like factor 9 (Klf9) is dysregulated in human and rodent cardiomyopathy. Both global and cardiac-specific Klf9-deficient mice displayed …
宋伟宏院士团队发现KLF9调控IFITM3表达参与Aβ产生-老年研究院…
Feb 17, 2025 · 本研究首次揭示了KLF9作为AD病理风险因子的重要作用，为深入解析Aβ生成的分子调控机制提供了新的理论依据，同时也为AD的靶向治疗策略提供了潜在的干预靶点。 我校 …
Krüppel-like factor KLF9 regulates PPAR - Nature
Aug 20, 2010 · Using promoter deletion and mutation analysis, we identified two KLF9-binding sites within the 0.6-kb region of the PPARγ2 proximal promoter, indicating that KLF9 interacts …
转录调节因子KLF9的研究进展
As a member of the Krüppel-like factors (KLFs) transcription factor family, KLF9 regulates the transcriptions of target genes by 3 C2H2 zinc finger motifs, binding to the GC rich region of the …
KLF9 KLF transcription factor 9 [ (human)] - National Center for ...
Feb 8, 2025 · KLF9 could down-regulate MMP9 expression to inhibit breast cancer metastasis. KLF9 status was associated with differentiation and vascular invasion expression and was …
KLF 转录因子 9（KLF9）基因 | MCE - MCE-生物活性分子大师
该基因编码的蛋白质是一种转录因子，可与位于启动子中的 GC 盒元件结合。 编码的蛋白质与单个 GC 盒的结合会抑制 mRNA 表达，而与串联重复的 GC 盒元件结合会激活转录。 [RefSeq 提 …
转录调节因子KLF9的研究进展-【维普期刊官网】- 中文期刊服务平台
摘要 KLF9是锌指蛋白Krüppel样转录因子(Krüppel-like factors,KLFs)家族的重要成员,通过C端的3个C2H2锌指蛋白结构,结合到靶基因启动子区富含GC的区域,调节靶基因的转录...