Dec 25, 2024 · KIR3DL1 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 1) is a Protein Coding gene. Diseases associated with KIR3DL1 include Graft …

Killer cell immunoglobulin-like receptor 3DL1 is a protein that in humans is encoded by the KIR3DL1 gene. [5] [6] [7] Killer cell immunoglobulin-like receptors (KIRs) are transmembrane …

Mar 4, 2025 · Title: Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients. HLA-Bw4 in association …

Oct 23, 2011 · Here we describe the structure of a human KIR3DL1 receptor bound to HLA-B*5701 complexed with a self-peptide. KIR3DL1 clamped around the carboxy-terminal end of …

KIR 基因簇的基因含量因单倍型而异，尽管在所有单倍型 (KIR3DL3、KIR3DP1、KIR3DL4、KIR3DL2) 中都发现了几个“框架”基因。 KIR 蛋白根据细胞外免疫球蛋白结构域 (2D 或 3D) 的数 …

Aug 25, 2021 · In this study, we focus on differential NK cell activity modulation through KIR3DL1 allotypes. KIR3DL1 expression levels varied according to their alleles. The combination of …

Nov 23, 2023 · HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19. Killer cell immunoglobulin-like receptor three domains long …

KIR3DL1 is a highly polymorphic receptor that binds to groups of HLAA and HLA-B allotypes that express the Bw4 epitope. The variation in KIR3DL1 allotypes manifests at a number of levels. …

studies indicate that KIR3DL1 expression may negatively regulate Treg function and suggest a previously undescribed target for improving immune tolerance for potential treatment of …

KIR3DL1 encodes a deduced 444-amino acid type I transmembrane protein. Sequence analysis showed that KIR3DL1 has a 21-amino acid signal peptide, an extracellular region containing …