K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis.

K-562 are lymphoblast cells isolated from the bone marrow of a 53-year-old chronic myelogenous leukemia patient. The K-562 cell line is widely used in immune system disorder and immunology research. Please fill out the form below to sign up for notification when the product becomes in stock. You were successfully signed up for notification.

The paired K562-s and K562-r clones are useful cell line models of sensitivity and resistance to a tyrosine kinase inhibitor used in the treatment of chronic myeloid leukemia. It has applications in immune system disorder research.

2025年2月7日 · K562 cells are classified as an erythroleukemia cell line, exhibiting properties of both erythroid and leukemic cells. Their large size, round shape, high nucleus-to-cytoplasm ratio, and chromosomal abnormalities, including the Philadelphia chromosome, are …

Complete karyotype characterization of the K562 cell line by combined application of G-banding, multiplex-fluorescence in situ hybridization, fluorescence in situ hybridization, and comparative genomic hybridization.

Here, we have characterized K562 cells focusing on the karyotype of cells in prolonged culture, regulation of expression of TfR in wildtype (WT) and doxorubicin-resistant cells, and responses to histone deacetylase inhibition (HDACi).

K562 is widely used in biomedical research. It is one of three tier-one cell lines of ENCODE and also most commonly used for large-scale CRISPR/Cas9 screens. Although its functional genomic and epigenomic characteristics have been extensively ...

2011年2月7日 · K562 is an erythroleukemia cell line that lacks HLA antigen expression. K562 cells have been shown to provide a cell contact-dependent co-stimulatory signal, enhancing the expansion of NK cells [52]. Combined with IL-2 and IL-15, …

The K562 CDX model (cell line derived xenograft), a relatively inexpensive subcutaneous (s.c.) mouse model, is used to observe the inhibition of tumor growth, the impact of endogenous or exogenous hormones, and animal survival.

K562, or K-562 (ATCC® CCL-243TM)*, cells are a chronic myelogenous leukemia (CML) continuous cell line originally isolated from the pleural effusion of a 53-year old female.