We focus the research interests on the development of anticancer agents. We have developed an assay system to do a large scale of screening tests to discover potential agents against cancers. In recent years, we have screened more than 4000 samples from both chemically synthetic compounds and natural products.

臺大位居世界頂尖大學之列，為永久珍藏及向國際展現本校豐碩的研究成果及學術能量，圖書館整合機構典藏（NTUR）與學術庫（AH）不同功能平台，成為臺大學術典藏NTU scholars。 期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。 To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

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Specialty： Clinical pharmacy, clinical pharmacokinetics and pharmacodynamics of antimicrobial agents.

Tunicamycin, an N-glycosylation inhibitor, causes unfolded protein response and is widely used as pharmacological inducer of endoplasmic reticulum stress. In this study, several designs were used to investigate the resistance mechanism to camptothecin and etoposide in hepatocellular carcinoma Hep3B cells.

The Journal of Gastroenterology and Hepatology is an international journal of scientific excellence in the fields of gastroenterology, hepatology and endoscopy, with particular emphasis on clinical research and continuing education in the Asian Pacific region.

Mar 7, 2024 · In conclusion, the data suggest that epi-reevesioside F inhibits the Na + /K + -ATPase and displays potent anti-NSCLC activity. Epi-reevesioside F sensitizes gefitinib-induced apoptosis through multiple pathways that converge on c-Myc downregulation.

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Mar 1, 2015 · Taxanes and vinca alkaloids are two groups of tubulin-binding agents in cancer chemotherapy. Besides tubulin binding, these groups of agents can also down-regulate protein levels of matrix metalloproteinase (MMP)-2 and -9, two important cancer-associated zinc-dependent endopeptidases in invasion and metastasis.

研究領域：藥物作用機轉研究 聯絡電話：(02)3366-8761 Email：[email protected]