2024年12月25日 · ITGB4 (Integrin Subunit Beta 4) is a Protein Coding gene. Diseases associated with ITGB4 include Epidermolysis Bullosa, Junctional 5B, With Pyloric Atresia and …

ITGB4 was transcriptionally activated by TFAP2A, and could promote LUAD progression and inhibit CD4 + /CD8 + T-cell infiltrations by activating the NF-κB signaling pathway. ITGB4 may …

2020年2月15日 · We developed two immunologic strategies to target ITGB4: ITGB4 protein-pulsed dendritic cells (ITGB4-DC) for vaccination and adoptive transfer of anti-CD3/anti-ITGB4 …

2017年1月13日 · Our results indicated that ITGB4 induces HCC cell growth and invasiveness and promotes EMT via a mechanism involving the transcription factor Slug. ITGB4 promoted tumor …

2023年10月3日 · Integrin β4 (ITGB4) is a major component of hemidesmosomes and a receptor molecule of laminin. Studies have shown that laminin-5 interacts with ITGB4 to activate RAC1 …

2024年8月6日 · Integrin β4 (ITGB4) is a transmembrane protein that functions as a mechanosensor, mediating the bidirectional exchange of information between the intracellular …

2024年1月3日 · The ITGB4 (Integrin subunit beta 4) gene encodes a receptor for laminins and its upregulation in tumor tissues is associated with poor prognosis. However, its role in glioma is …

The ITGB4 gene provides instructions for making one part (the β4 subunit) of a protein known as an integrin. Learn about this gene and related health conditions.

Itgb4 protein remains expressed in the early stages of peripheral regeneration and subsequent myelination. integrin beta4 is implicated in and associated with p53 in autophagy of lung …

ITGB4-overexpressing CAF-conditioned medium promoted the proliferation, epithelial-to-mesenchymal transition, and invasion of breast cancer cells. In a co-transplant mouse model, …