
IRS2GoApp - Internal Revenue Service
2024年4月18日 · Check the status of your federal income tax refund using IRS2Go. You can check your refund status within 24 hours after we receive your e-filed return, or about four (4) …
IRS2 Gene - GeneCards | IRS2 Protein | IRS2 Antibody
2024年12月25日 · IRS2 (Insulin Receptor Substrate 2) is a Protein Coding gene. Diseases associated with IRS2 include Type 2 Diabetes Mellitus and Polycystic Ovary Syndrome. …
IRS2 - Wikipedia
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a …
IRS2 - an overview | ScienceDirect Topics
In type 2-diabetes and impaired glucose tolerance, the muscle, fat and liver become resistant to insulin, and recent developments place dysregulation of insulin receptor substrate (IRS) …
Targeting type 2 diabetes: lessons from a knockout model of ...
Insulin receptor substrate 2 (IRS2) is a widely expressed protein that regulates crucial biological processes including glucose metabolism, protein synthesis, and cell survival. IRS2 is part of …
Differential hepatic distribution of insulin receptor ...
2016年10月6日 · We demonstrate that hepatic Irs2-knockout mice develop ‘selective insulin resistance’, whereas mice lacking in Irs1, or both Irs1 and Irs2, develop ‘total insulin resistance’.
IRS2 insulin receptor substrate 2 [ Homo sapiens (human) ]
2025年3月4日 · Title: Enhancer RNA IRS2e is essential for IRS2 expression and the oncogenic properties in oral squamous cell carcinoma. Identification of the ageing-related prognostic …
Role of IRS-2 in insulin and cytokine signalling - Nature
1995年9月14日 · Alignment of the sequences of IRS-2 and IRS-1 revealed a highly conserved amino terminus containing a pleckstrin-homology domain and a phos-photyrosine-binding …
The Insulin Receptor Adaptor IRS2 is an APC/C Substrate That ...
Insulin receptor substrate 2 (IRS2) is an essential adaptor that mediates signaling downstream of the insulin receptor and other receptor tyrosine kinases. Transduction through IRS2 …
IRS2 insulin receptor substrate 2 - NIH Genetic Testing ...
2024年12月9日 · This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by …