
Interleukin 4 - Wikipedia
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …
Recent advances in understanding the role of IL-4 signaling
Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, but this …
Interleukin - StatPearls - NCBI Bookshelf - National Center for ...
2022年8月22日 · Interleukin-4 (IL-4) CD4+T cells (Th2) synthesize IL-4, and it acts on both B and T cells. It is a B-cell growth factor and causes IgE and IgG1 isotype selection. It causes Th2 …
Interleukin-4: A Cytokine to Remember - PMC - PubMed Central …
Lipopolysaccharide-induced interleukin (IL)-4 receptor-alpha expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice. Brain, …
Interleukin 4 - an overview | ScienceDirect Topics
Interleukin-4 is a cytokine that is produced by various cells and plays a role in exerting anti-inflammatory effects during infections like tuberculosis. AI generated definition based on: …
Regulation of inflammation by interleukin-4: a review of …
Keywords: alternative splicing, interelukin-4 receptor, interleukin-4 signaling, alternative macrophage activation. Abstract. Studies of IL-4 have revealed a wealth of information on the …
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 …
2018年6月6日 · Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They play important roles in regulating the responses of lymphocytes, …
Interleukin-4 (IL-4) pathway - PubMed
2005年7月19日 · Interleukin-4 (IL-4) is a cytokine produced by T(H)2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which …
Interleukin 4: signalling mechanisms and control of T cell ...
Interleukin 4 (IL-4) is a pleiotropic type I cytokine that controls both growth and differentiation among haemopoietic and non-haemopoietic cells. Its receptor is a heterodimer. One chain, the …
Recent advances in understanding the role of IL-4 signaling
2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …
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