Monoclonal Antibody for studying InsR-alpha. Validated for WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Insulin Receptor α (D3U7I) Rabbit Monoclonal …

2024年12月25日 · INSR (Insulin Receptor) is a Protein Coding gene. Diseases associated with INSR include Donohue Syndrome and Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, …

Insulin (InsR) and insulin-like growth factor-1 (IGF1R) receptors mediate the metabolic and growth-promoting actions of insulin and IGF1/IGF2, respectively. Evidence accumulated in …

2019年11月23日 · Insulin and insulin-like growth factor-1 (IGF1) have important roles in breast cancer development. The recent identification of nuclear insulin (INSR) and IGF1 (IGF1R) …

2023年10月26日 · Insulin resistance is associated with many pathological conditions, and an in-depth understanding of the mechanisms involved is necessary to improve insulin sensitivity. …

Although the insulin receptor (INSR) and IGF1 receptor (IGF1R) share the vast majority of their downstream cytoplasmic mediators, most evidence is consistent with the notion that INSR …

Structurally and functionally related receptors to the INSR in mammalian organisms are the insulin‐like growth factor 1 receptor (IGF1R) and the insulin receptor‐related receptor (INSRR). …

胰岛素或其他配体结合到这个受体上，激活胰岛素信号通路，该通路调节葡萄糖的摄取和释放，以及碳水化合物的合成和储存，脂质和蛋白质。 这个基因中的突变导致了遗传性严重胰岛素抵 …

2019年11月29日 · Our recent analysis of the transcriptional controls affecting expression of the Drosophila insulin receptor gene indicates that a remarkable amount of DNA is dedicated to …

2021年4月2日 · Co-transfection experiments in breast cancer cell lines harboring specific disruptions of either the IGF1R or InsR allowed us to investigate the impact of nuclear InsR on …