
IL6ST Gene - GeneCards | IL6RB Protein | IL6RB Antibody
2024年12月25日 · IL6ST (Interleukin 6 Cytokine Family Signal Transducer) is a Protein Coding gene. Diseases associated with IL6ST include Hyper-Ige Syndrome 4B, Autosomal Recessive, …
Glycoprotein 130 - Wikipedia
Glycoprotein 130 (also known as gp130, IL6ST, IL6R-beta or CD130) is a transmembrane protein which is the founding member of the class of tall cytokine receptors. It forms one subunit of the …
IL6ST interleukin 6 cytokine family signal transducer [ (human)]
Bioinformatics Analysis Identifies IL6ST as a Potential Tumor Suppressor Gene for Triple-Negative Breast Cancer. Mosaic IL6ST variant inducing constitutive GP130 cytokine receptor …
Il6st interleukin 6 signal transducer [ (house mouse)]
2025年2月8日 · Contributes to interleukin-11 binding activity and interleukin-11 receptor activity. Involved in interleukin-6-mediated signaling pathway; intestinal epithelial cell development; …
INTERLEUKIN 6 CYTOKINE FAMILY SIGNAL TRANSDUCER; IL6ST
Rodriguez, C., Grosgeorge, J., Nguyen, V. C., Gaudray, P., Theillet, C. Human gp130 transducer chain gene (IL6ST) is localized to chromosome band 5q11 and possesses a pseudogene on …
IL6ST interleukin 6 cytokine family signal transducer
2024年9月19日 · The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated …
Structural insights into IL-11-mediated signalling and human IL6ST ...
2024年3月7日 · We explore how mutations in the IL6ST gene encoding for gp130, which cause severe immune deficiencies in humans, impair signalling without blocking cytokine binding. We …
Dominant-negative mutations in human IL6ST underlie hyper-IgE …
2020年6月1日 · Autosomal dominant hyper-IgE syndrome (AD-HIES) is typically caused by dominant-negative (DN) STAT3 mutations. Patients suffer from cold staphylococcal lesions …
New Dominant-Negative IL6ST Variants Expand the …
A new pathogenic variant of the IL6ST gene was identified in P1, P2, P3, P4, P5, P6, and P7 by the targeted sequencing of 84 genes implicated in monogenic human inborn errors of innate …
IL6ST: A Novel Therapeutic Target for Managing and Treating …
Interleukin 6 cytokine family signal transducer (IL6ST) is a protein that serves as a co-receptor for interleukin-6 (IL-6), interleukin-11 (IL-11), and related cytokines.