Interleukin-6 receptor - Wikipedia
Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor …
IL6R Gene - GeneCards | IL6RA Protein | IL6RA Antibody
Dec 25, 2024 · IL6R (Interleukin 6 Receptor) is a Protein Coding gene. Diseases associated with IL6R include Hyper-Ige Syndrome 5, Autosomal Recessive, With Recurrent Infections and …
白介素IL-6信号转导及其通路研究概述 - 知乎 - 知乎专栏
IL-6结合受体有两种，一种是特异性受体 IL-6R （80kDa I型跨膜蛋白），另一种是gp130，是IL-6家族细胞因子的所有成员的常见受体亚单位。 gp130可以在所有细胞表达，但IL-6R的表达受 …
白细胞介素-6受体 - 百度百科
α链可从膜表面脱落或由于RNA的不同剪接而形成sIL-6R，能与IL-6结合为复合物，通过与膜型gp130结合而增强IL-6的生物学作用。 白细胞介素-6受体是医学术语。
IL-6R (白细胞介素-6 受体) - MCE-生物活性分子大师
Interleukin-6 receptor (IL-6R) is a receptor for IL-6, belonging to the type I cytokine receptor family, subfamily 3. IL-6 is a potent pleiotropic cytokine that regulates cell growth and …
The soluble interleukin 6 receptor: mechanisms of production …
Elevated sIL-6R levels have been documented in numerous clinical conditions indicating that its production is coordinated as part of a disease response. Thus, sIL-6R has the potential to …
IL-6 通路 | Cell Signaling Technology
IL-6 信号转导异常参与了自身免疫疾病、炎症和部分癌症（如前列腺癌和多发性骨髓瘤）的发病机理。 目前 Jak 抑制剂在多发性骨髓瘤模型中进行测试。 Stat3 可充当一种致癌基因，并在许 …
Targeting IL-6 trans-signalling: past, present and future prospects
Apr 17, 2023 · Classical IL-6 signalling involves the binding of IL-6 to the membrane-bound IL-6 receptor α-subunit (hereafter termed ‘mIL-6R’) and glycoprotein 130 (gp130) signal …
Interleukin-6 and its receptors: a highly regulated and ... - PubMed
IL-6 induces intracellular signaling pathways after binding to its membrane-bound receptor (IL-6R), which is only expressed on hepatocytes and certain subpopulations of leukocytes (classic …
白细胞介素 6 受体（IL6R）基因 | MCE - MCE-生物活性分子 ...
IL6 受体是一种蛋白质复合物，由这种蛋白质和白介素 6 信号转导 (IL6ST/GP130/IL6-beta) 组成，后者是许多其他细胞因子共有的受体亚基。 IL6 和该受体的失调产生与许多疾病的发病机制 …