白介素33（interleukin 33，IL-33）是由人源基因 IL33编码的蛋白，其是IL-1家族成员，能有效驱动辅助因子Th2的产生。 白介素33是ST2的配体之一。 在非活性状态下，IL-33以前体形式（全 …

Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. [5] Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated …

知乎，中文互联网高质量的问答社区和创作者聚集的原创内容平台，于 2011 年 1 月正式上线，以「让人们更好的分享知识、经验和见解，找到自己的解答」为品牌使命。知乎凭借认真、专业 …

2024年12月25日 · Complete information for IL33 gene (Protein Coding), Interleukin 33, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human …

2016年9月19日 · Il33 −/− mice with dextran sodium sulfate (DSS)-induced acute colitis showed decreased mortality and inflammation but had delayed recovery at later phases 154.

The critical function of IL-33/ST2 signaling in allergic inflammation is illustrated by the fact that IL33 and IL1RL1 are among the most highly replicated susceptibility loci for asthma. In this …

2022年8月1日 · Cigarette smoke and infection are the major drivers of COPD. Loss of Il33 protects mice from smoke-induced exaggerated inflammatory responses to influenza virus …

IL-33 may be important for allergic airway diseases in humans. Indeed, the IL33 and ST2/IL1RL1 genes were found to be associated with asthma and allergic rhinitis in several GWAS studies …

Analysis of patient samples and studies in murine models support an important role of IL-33/ST2 signaling in allergic inflammation in different tissues (lung, nasopharynx, skin) and diseases …

2022年9月16日 · 若要将IL33/ST2最大限度运用到肿瘤诊断及治疗，关键在于肿瘤微环境的研究及如何平衡其在Th1/Th2免疫应答中的作用，这或将成为未来肿瘤研究的关注点。