Interleukin 16 (IL-16), formerly known as lymphocyte chemoattractant factor or LCF, is a pro-inflammatory cytokine that is chemotactic for CD4 + T lymphocytes, monocytes, and eosinophils.

Dec 25, 2024 · IL16 (Interleukin 16) is a Protein Coding gene. Diseases associated with IL16 include Whipple Disease and Graves Disease . Among its related pathways are MIF Mediated …

IL-16 is constitutively produced by peripheral blood monocytes, epithelial cells, epidermal Langerhans cells, mast cells, macrophages, DCs, CD8 + T, CD4 + T, and eosinophils. The …

Interleukin-16 (IL-16) is generated as a precursor molecule that is cleaved by caspase-3 to produce a pro-IL-16 molecule that functions as a regulator of T cell growth, and a secreted …

Herein, we review the body of evidence supporting a role for IL-16 in infectious and immune-mediated inflammatory disorders and explore the known and possible mechanism of actions in …

IL-16 selectively regulates migration of all CD4 expressing T cells regardless of their activation state, which is of critical importance for immune modulation and potential therapy of MS.

Feb 12, 2024 · Interleukin-16 (IL-16) stands out as a multifaceted cytokine with a complex role in regulating the immune system. Discovered by Dr. David Cruikshank at Boston University, IL …

Mar 10, 2025 · In terms of the prognostic potential of IL-16, we found that low IL16 expression was significantly correlated with inferior survival of patients in 10 out of 31 TCGA cancer types …

High-Dose Dexamethasone Alters the Increase in Interleukin-16 Level in Adult Immune Thrombocytopenia. The regional up-regulation of IL-16 in the skin is not only associated with …

Dec 10, 2024 · Knockdown of interleukin 16 (IL16) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells: PubMed