IL-1家族信号途径及功能 - 知乎 - 知乎专栏
一、il-1家族配体、受体成员白细胞介素-1（il-1）家族细胞因子是先天免疫系统和适应性免疫系统中的关键信号分子，介导对多种刺激的炎症反应。家族配体成员有：il-1α、il-1β、 il-1ra、 il …
Interleukin-1 family - Wikipedia
The soluble form is produced by hepatocytes and regulated by pro-inflammatory cytokines (IL1-β and a combination of IL1-β and IL-6) and other acute phase proteins. The intracellular form …
重点推荐 | IL-1β：参与先天免疫的重要促炎细胞因子 - 知乎
il-1β作为一种关键的促炎细胞因子，参与多种自身免疫性炎症反应和多种细胞活动，包括细胞增殖、分化和凋亡。il-1β与il1-α和il18一起，通过多种下游机制协调免疫反应。il-1β参与il-6和tnf-α …
白介素-1族 - 维基百科，自由的百科全书
白细胞介素1族包括11种细胞因子，它们组成了促炎细胞因子的复杂网络。 这些细胞因子通过调控白细胞和内皮细胞的整合素的表达，启动和控制炎症反应。 [2]由于il-1α和il-1β最先发现而且 …
白细胞介素-1 - 百度百科
最初测定的为 IL1和IL2。IL1属于monokine，以前曾以淋巴细胞活化因子（lymphocyte activating factor）命名。细胞促进 蛋白质 （mitogenic protein）以及B细胞活化因子（B cell－activating …
白细胞介素-1β(Interleukin—1β,IL-1β) - 知乎 - 知乎专栏
白细胞介素 是由多种细胞产生并作用于多种细胞的一类细胞因子，它和血细胞生长因子同属细胞因子。 两者相互协调，相互作用，共同完成造血和免疫调节功能。白细胞介素在传递信息，激 …
The IL-1 family: regulators of immunity - Nature
Jan 18, 2010 · Interleukin-1 (IL-1), which as its name suggests was the first interleukin to be described, possesses many biological activities. Indeed, before its molecular identification in …
Overview of the IL-1 family in innate inflammation and acquired ...
Both the TLR and IL-1 families nonspecifically augment antigen recognition and activate lymphocyte function. The lymphocyte-activating function of purified IL-1 was first described in …
Interleukin-1 (IL-1) Pathway | Science Signaling - AAAS
The interleukin-1 (IL-1) family of cytokines comprises 11 proteins (IL-1F1 to IL-1F11) encoded by 11 distinct genes (IL1A, IL1B, IL1RN, IL18, and IL1F5 to IL1F11 in humans, Il1A to Ilf11 in …
The IL-1 family: regulators of immunity - PubMed
Over recent years it has become increasingly clear that innate immune responses can shape the adaptive immune response. Among the most potent molecules of the innate immune system …