Interleukin 7 (IL-7) is a protein [5] that in humans is encoded by the IL7 gene. [6] [7] [8] IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is …

2002年6月1日 · IL-7 treatment of mice leads to mobilization of hematopoietic progenitors from the marrow to the spleen, thus increasing splenic colony-forming units and diminishing …

2021年12月1日 · Interleukin-7 (IL-7), a molecule known for its growth-promoting effects on progenitors of B cells, remains one of the most extensively studied cytokines. It ...

2019年11月19日 · In their Review, Barata, Durum and Seddon describe IL-7’s key homeostatic functions and how its dysregulation can lead to autoinflammatory disease and cancer.

Overview: IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind Type I cytokine receptors. It is produced by stromal cells and is required for development and …

Interleukin (IL)-7 is required for T-cell development as well as for the survival and homeostasis of mature T-cells. In the thymus, the double negative (DN) CD4(-) CD8(-) thymocyte progenitor …

Interleukin-7 (IL-7) is a biological compound that plays a role in maintaining the balance of T cells, specifically by promoting the growth of both naïve and memory T cells. It has shown potential …

Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the adaptive immune system. It promotes lymphocyte development in the thymus and maintains survival of …

IL-7 is critical for the development, maintenance, and proliferation of T lymphocytes, highlighting its potential role as an adjuvant in the development of cancer vaccines.

2011年4月21日 · Interleukin-7 (IL-7) induces T cell proliferation and enhances antigen-specific immune responses: attributes that pinpoint its value as a potential therapeutic agent.