
Interleukin 25 - Wikipedia
Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) [5] – is a protein that in humans is encoded by the IL25 gene on chromosome 14. [6] [7] [8] IL-25 was discovered in 2001 and is made up of 177 amino acids. [6]
IL-25 (IL-17E) in epithelial immunology and pathophysiology
IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25 exclusively was shown to strongly induce expression of the cytokines associated with type 2 immunity.
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Interleukin 25 and its biological features and function in intestinal ...
Interleukin 25 (IL-25), also known as IL-17E, is a member of the IL-17 cytokine family and an important regulator of the type 2 immune response. Accumulating evidence suggests that IL-25 interacts with diverse immune as well as non-immune cells and ...
New insights into the function of Interleukin-25 in disease ...
Apr 1, 2023 · IL-25 is an alarm signal generated upon cell injury or tissue damage to activate immune cells through the interaction with IL-17RA and IL-17RB receptors.
IL-25 regulates Th17 function in autoimmune inflammation - PMC
Interleukin (IL)-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. We now show that IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells.
Roles of IL-25 in Type 2 Inflammation and Autoimmune …
May 27, 2021 · IL-25 binds to its receptor composed of IL-17 receptor A (IL-17RA) and IL-17 receptor B (IL-17RB) for signal transduction. IL-25 has been implicated as a type 2 cytokine and can induce the production of IL-4, IL-5 and IL-13, which in …
IL-25 in allergic inflammation - PubMed
The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer. This review summarizes the literature on IL-25 and discusses the unsolved questions.
Interleukin 25 - an overview | ScienceDirect Topics
Interleukin-25 (IL-25), the newest member of the IL-17 cytokine family, initiates, promotes, and augments Th2 cell-mediated immune responses, thereby contributing to allergic disease and defense against helminthic parasites.
Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context ...
Mar 12, 2025 · IL-25, previously known as IL-17E, is a member of the IL-17 cytokine family that contains the structurally related proteins IL-17A–IL-17F 10. While best studied for IL-17A and IL-17F, this ...
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