Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) [5] – is a protein that in humans is encoded by the IL25 gene on chromosome 14. [6] [7] [8] IL-25 was discovered in 2001 and is made up of 177 amino acids. [6]

IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25 exclusively was shown to strongly induce expression of the cytokines associated with type 2 immunity.

Interleukin 25 (IL-25), also known as IL-17E, is a member of the IL-17 cytokine family and an important regulator of the type 2 immune response. Accumulating evidence suggests that IL-25 interacts with diverse immune as well as non-immune cells and ...

Interleukin (IL)-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. We now show that IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells.

2023年4月1日 · IL-25 is an alarm signal generated upon cell injury or tissue damage to activate immune cells through the interaction with IL-17RA and IL-17RB receptors.

2024年12月25日 · IL25 (Interleukin 25) is a Protein Coding gene. Diseases associated with IL25 include Psoriasis 8 and Inflammatory Bowel Disease 29. Among its related pathways are IL-17 Family Signaling Pathways and Cytokine Signaling in Immune system.

2000年12月18日 · We have characterized a cytokine produced by Th2 cells, designated as IL-25. Infusion of mice with IL-25 induced IL-4, IL-5, and IL-13 gene expression.

The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer. This review summarizes the literature on IL-25 and discusses the unsolved questions.

5 天之前 · IL-25, previously known as IL-17E, is a member of the IL-17 cytokine family that contains the structurally related proteins IL-17A–IL-17F 10. While best studied for IL-17A and IL-17F, this ...

Interleukin-25 (IL-25) is a recently identified member of the IL-17 cytokine family. It has the ability to influence innate and adaptative immunity.