Clinical significance of isolated IgE deficiency - UpToDate
2024年11月15日 · Selective immunoglobulin (Ig)E deficiency is defined as a significant decrease in the levels of IgE (<2.5 international units/mL) in a patient whose other immunoglobulin levels, including IgG, IgG subclasses, and IgA levels, are normal.
Low IgE concentration - American Academy of Allergy, Asthma
BACKGROUND: Immunoglobulin E (IgE) deficiency (<2.5 kU/L) has unclear clinical significance. Very little is known about the clinical characteristics of IgE deficiency in patients with Common Variable Immunodeficiency (CVID).
Low immunoglobulin E flags two distinct types of immune …
Keywords: allergy, antibody deficiency, IgE, IgG subclass, immunodeficiency. Introduction. Immunoglobulin E (IgE) is best known for its association with allergic disease due to the activation of mast cells via the Fc‐ε receptor 1.
IgE deficiency: immunodeficiency, atopy & malignancy
2023年10月18日 · Until recently, a very low or absent serum IgE level (IgE < 2.5 kU/L; also known as IgE deficiency) was considered normal. However, recent studies have shown that patients with IgE deficiency have significantly increased rates and risk for cancer.
The other side of the coin: IgE deficiency, a susceptibility factor …
2020年11月20日 · Recent prospective and retrospective studies show that having very low IgE levels, such as those seen in IgE deficiency (IgE<2.5 kU/L), is not without clinical consequences. Patients with ultra-low IgE levels have an elevated risk of cancer of any type.
The other side of the coin: IgE deficiency, a susceptibility factor …
Recent prospective and retrospective studies show that having very low IgE levels, such as those seen in IgE deficiency (IgE<2.5 kU/L), is not without clinical consequences. Patients with ultra-low IgE levels have an elevated risk of cancer of any type.
Understanding Low Immunoglobulin E Test Results - MediSearch
When immunoglobulin E (IgE) levels are low, it can indicate an underlying condition or immune dysregulation. Here are some key points about low IgE levels: Low IgE, defined as <2 kU/L, is called IgE deficiency or selective IgE deficiency when other immunoglobulin levels are …
The Very Low IgE Producer: Allergology, Genetics, …
Patients with allergic rhinitis or peanut anaphylaxis but low or undetectable allergen-specific IgE levels must therefore be reconsidered considering their total IgE levels. Low IgE producers have been also associated with common variable immunodeficiency, lung diseases, and malignancies.
Selective IgE deficiency, immune dysregulation, and autoimmunity
Selective IgE deficiency (IgED) is currently defined as a significant decrease in serum levels of IgE (<2 kIU/L) in a patient whose other immunoglobulin levels are normal. There are no published large-scale epidemiological studies regarding the prevalence of and clinical features of IgED.
What is an IgE deficiency? - Answr
2024年12月16日 · An IgE deficiency, specifically a selective IgE deficiency, is a condition characterized by significantly low levels of immunoglobulin E (IgE) in the blood while other immunoglobulin levels remain normal.