2024年12月25日 · IFI35 (Interferon Induced Protein 35) is a Protein Coding gene. Diseases associated with IFI35 include Stomatitis and Mouth Disease. Among its related pathways are Cytokine Signaling in Immune system and Antiviral mechanism by IFN-stimulated genes. An important paralog of this gene is NMI.

70110 Ensembl ENSG00000068079 ENSMUSG00000010358 UniProt P80217 Q9D8C4 RefSeq (mRNA) NM_005533 NM_001330230 NM_027320 RefSeq (protein) NP_001317159 NP_005524 NP_081596 Location (UCSC) Chr 17: 43.01 – 43.01 Mb Chr 11: 101.34 – 101.35 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interferon-induced 35 kDa protein is a …

2024年4月9日 · Targeting IFI35 effectively suppressed in vivo tumor growth and prolonged survival of orthotopic xenograft-bearing mice.

2023年6月28日 · Our findings identify IFI35 as a new biomarker that can enhance the proliferation and function of CD8 + T cells, as well as increase the efficacy of CAR-T cells against colorectal cancer cells.

2021年5月10日 · Here we show that interferon induced protein 35 (IFI35) inhibits swine (H3N2) influenza virus replication by directly interacting with the viral protein NS1. IFI35 binds more preferentially to the effector domain of NS1 (128-207aa) than to the viral RNA sensor RIG-I.

Interferon-induced protein 35 (IFI35) is an IFN-γ-induced protein that plays important roles in the antivirus-related immune-inflammatory response. In this study, we tested whether overexpression IFI35 affects the proliferation and migration of endothelial cells (ECs) and re-endothelialization.

2023年6月28日 · Our findings identify IFI35 as a new biomarker that can enhance the proliferation and function of CD8 + T cells, as well as increase the efficacy of CAR-T cells against colorectal cancer cells. We bear witness the striking breakthroughs in using immune checkpoint inhibitors (ICIs) for diverse cancers, including CRC [1, 2].

interferon-induced 35 kDa protein, IFP 35, ifi-35. IFP35 family proteins promote neuroinflammation and multiple sclerosis. IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis. IFI35 enhances proliferation of mesangial cells and is regulated by MBD2 in lupus nephritis.

2025年2月8日 · Enables identical protein binding activity. Involved in several processes, including macrophage activation involved in immune response; negative regulation of non-canonical NF-kappaB signal transduction; and positive regulation of defense response.

2013年10月29日 · IFI35 rescues VSV infection by negatively regulating the host antiviral response. Since our results demonstrated that IFI35 depletion led to reduced VSV RNA transcription and replication, we investigated whether IFI35 colocalizes or interacts with the VSV transcription and replication machinery.