
ICAM-1: A master regulator of cellular responses in inflammation ...
ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for regulating leukocyte recruitment from circulation to sites of inflammation. However, in addition to vascular endothelial cells, ICAM-1 expression is also robustly ...
ICAM1 Gene - GeneCards | ICAM1 Protein | ICAM1 Antibody
2024年12月25日 · ICAM1 (Intercellular Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with ICAM1 include Malaria and Cerebral Malaria. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling and Cytokine Signaling in Immune system.
ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and ...
2023年8月1日 · ICAM-1, an immunoglobulin (Ig)-like cell adhesion molecule, is expressed by two cell types: leukocytes and endothelial cells. ICAM-1 expression is mainly controlled by transcription. ICAM-1 plays a vital role in inflammation and …
ICAM-1: role in inflammation and in the regulation of vascular ...
In their paper, Sumagin et al. have examined the role of ICAM-1 and the possible role of a leukocyte-endothelium interaction in the regulation of vascular permeability. During inflammation development, two major events occur.
ICAM-1: Isoforms and Phenotypes - PMC - PubMed Central (PMC)
Intercellular adhesion molecule-1 (ICAM-1) plays an important role in leukocyte trafficking, immunological synapse formation and, numerous cellular immune responses.
Intercellular Adhesion Molecule 1 (ICAM-1): An Inflammatory
2024年9月15日 · Intercellular adhesion molecule 1 (ICAM-1/CD54), a transmembrane glycoprotein, has been considered as one of the most important adhesion molecules during leukocyte recruitment. It is encoded by the ICAM1 gene and plays a central role in inflammation.
ICAM1 intercellular adhesion molecule 1 [ (human)]
ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis. Inactivation of ICAM1 inhibits metastasis and improves the prognosis of Ewing's sarcoma. Genome-wide identification of lncRNAs and mRNAs differentially expressed in human vascular smooth muscle cells stimulated by high phosphorus.
ICAM-1: Isoforms and Phenotypes - American Association of …
2014年5月15日 · ICAM-1 is an iconic marker of inflammation in EAE and multiple sclerosis, with elevated expression at lesion sites on endothelial cells and on infiltrating and resident CNS cells (7, 57, 58).
Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A ...
2021年12月1日 · Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied inducible cell adhesion molecule which is responsible for several immune functions. The molecule is constitutively expressed over the cell surface and is regulated up / down in response to inflammatory mediators.
ICAM-1 - an overview | ScienceDirect Topics
ICAM-1 mediates the adhesion and infiltration of leucocytes by recognition with the ligand lymphocyte function-associated antigen-1 (LFA-1). In addition, the ICAM-1/LFA-1 interaction plays an important role in the formation of the immunological synapse between T cells and APCs.
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