2024年12月25日 · IL1RN (Interleukin 1 Receptor Antagonist) is a Protein Coding gene. Diseases associated with IL1RN include Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis …

Interleukin-1 receptor antagonist (IL-1ra) is an endogenous immunomodulatory cytokine encoded by IL1RN on chromosome 2 that inhibits the actions of IL-1α and IL-1β [1, 2]. IL-1ra is …

Authors demonstrated that methionine deprivation inhibited glioma cell proliferation via downregulating interleukin 1 receptor antagonist (IL1RN) both in vitro and in vivo, methionine …

2023年4月1日 · IL1RA gene (IL1RN) carries polymorphisms in a variety of squamous cell carcinomas. IL1RA exhibits inhibitory effects on various squamous cell carcinomas. …

2022年6月21日 · IL-1α, IL-1β and IL-1RA are highly regulated inflammatory mediators involved in damage- and pathogen-associated molecular pattern (DAMPs and PAMPs), and cell death …

2014年3月1日 · The IL1RN gene produces two forms of IL1RN: intracellular (icIL1RN) and secreted (sIL1RN) which are controlled by different promoter regions (Redlitz et al., 2004). …

Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid …

2024年6月14日 · The data suggest that the IL1RN pathway modulates the severity of coronavirus disease 2019 (COVID-19) via endogenous anti-inflammatory mechanisms. Keywords: IL1RN; …

2009年6月4日 · Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations of …

2025年2月8日 · Title: Exosome microRNA-125a-5p derived from epithelium promotes M1 macrophage polarization by targeting IL1RN in chronic obstructive pulmonary disease.