2024年12月25日 · IL1R1 (Interleukin 1 Receptor Type 1) is a Protein Coding gene. Diseases associated with IL1R1 include Chronic Recurrent Multifocal Osteomyelitis 3 and Schnitzler Syndrome . Among its related pathways are Bacterial infections in …

2023年7月17日 · Here we identify a pro-tumorigenic IL1R1+, IL-1-high-signaling subtype of fibroblasts, using multiple colorectal cancer (CRC) patient single cell sequencing datasets.

IL1R1 is a prognostic marker in Glioblastoma multiforme Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected.

IL1R1 gene variants associate with disease susceptibility to IgG4-related periaortitis/periarteritis in IgG4-related disease. Expression of obesity- and type-2 diabetes-associated genes in omental adipose tissue of individuals with obesity.

2024年10月5日 · IL1R1 is a membrane protein located on the cell surface. It consists of three extracellular domains and one intracellular domain. The extracellular domains of IL1R1 bind to interleukin-1 (IL-1), while the intracellular domain is responsible for …

We used a genetic knockin reporter system in mice to track and reciprocally delete or express IL-1 receptor 1 (IL-1R1) in specific cell types, including endothelial cells, ventricular cells, peripheral myeloid cells, microglia, astrocytes, and neurons.

2010年1月18日 · IL-1 family members promote the activity of cells of the innate immune system, such as neutrophils, eosinophils, basophils, mast cells and natural killer cells. IL-1 family members also have...

2024年11月19日 · Interleukin-1 (IL-1) is a pro-inflammatory cytokine that exerts a wide range of neurological and immunological effects throughout the central nervous system (CNS) and is associated with the etiology of affective and cognitive disorders.

We used a genetic knockin reporter system in mice to track and reciprocally delete or express IL-1 receptor 1 (IL-1R1) in specific cell types, including endothelial cells, ventricular cells, peripheral myeloid cells, microglia, astrocytes, and neurons.

2024年12月27日 · We found that non-telomeric TRF2 transcriptionally activated interleukin-1-receptor type-1 (IL1R1) in a telomere-dependent fashion: resulting NF-kappaB (p65)-phosphorylation led to the upregulation of downstream cytokines.