
靶点梳理:白细胞介素-22 (IL-22) - 知乎 - 知乎专栏
IL-22BP与IL-22的亲和力高20 - 1000倍,是IL-22生物活性的内源性抑制剂。 IL-22与其受体结合后,通过 JAK-STAT通路,主要激活STAT3,也可激活STAT1和STAT5, IL-22还可触发NF …
IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 Biology
In this review, we will focus on IL-22BP, including its regulation, role in IL-22 biology and inflammation, and promise as a therapeutic. IL-22 can be protective or pathogenic, depending …
Interleukin 22 - Wikipedia
IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein, IL …
IL-22 Binding Protein (IL-22BP) in the Regulation of IL-22 Biology
2021年11月16日 · In this review, we will focus on IL-22BP, including its regulation, role in IL-22 biology and inflammation, and promise as a therapeutic. IL-22 can be protective or pathogenic, …
IL22RA2 - Wikipedia
Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22 binding protein (IL-22BP) is a naturally secreted monomeric protein acting as an interleukin-22 (IL-22) …
Interleukin-22: immunobiology and pathology - PMC - PubMed …
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T-helper (Th)-17 cells, γδ T cells, NKT cells and newly described innate lymphoid cells (ILCs). …
ELISA专题 | 白细胞介素-22 ( Interleukin-22 , IL-22) - 知乎
il-22除了其功能受体外,还有一种内源性拮抗剂 il-22结合蛋白 (il-22bp,又称il-22ra2)。il-22bp与il-22的亲和力高20 - 1000倍,是il-22生物活性的内源性抑制剂。 IL-22BP与IL-22的亲和力高20 - …
I don’t know about you, but I’m feeling IL-22 - ScienceDirect
2024年12月1日 · IL-22 is a cytokine in the IL-10 cytokine family that has garnered increased attention in recent years due to its intimate link in promoting resolution of inflammatory insults, …
白细胞介素-22 (IL-22) | 重组蛋白 | MCE - MCE-生物活性 ...
il-22 蛋白是一种分泌型 il-10 家族细胞因子,参与炎症反应、活性氧代谢过程以及上皮细胞的再生和扩散。 IL-22 通过 STAT3、ERK1/2、MAPK 和 PI3K / AKT 通路促进细胞存活和增殖。
Interleukin-22 alleviates metabolic disorders and restores mucosal ...
2014年8月6日 · Interleukin (IL)-22 exerts essential roles in eliciting antimicrobial immunity and maintaining mucosal barrier integrity within the intestine 6, 7. Here we investigate the...