Choose from 1 of 226 IFN gamma antibodies, which have been validated in experiments with 7996 publications and 1793 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.

IFN-γ (D3H2) XP ® Rabbit mAb recognizes endogenous levels of total IFN-γ protein. Monoclonal antibody is produced by immunizing animals with recombinant human IFN-γ protein. IFN-γ plays key roles in both the innate and adaptive immune response. IFN-γ activates the cytotoxic activity of innate immune cells, such as macrophages and NK cells (1,2).

Choose from 1 of 226 IFN gamma antibodies, which have been validated in experiments with 7996 publications and 1793 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.

IFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance.

Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.

2017年2月28日 · IFN-γ Antibody (E-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects interferon gamma (IFN-γ) of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and …

Clone REA600 recognizes the human interferon gamma (IFN-γ) antigen, a cytokine of type II class interferons. IFN-γ is produced by lymphocytes that are involved in inflammatory immune responses.

We offer IFN-gamma Antibodies for use in common research applications: Blocking/Neutralizing, Chemiluminescence Immunoassay, Cytokine immunotrapping Assay, ELISA, ELISA Capture (M

IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines.

Test Use: Increased susceptibility to BCG or nontuberculous mycobacteria (NTM) may be caused by genetic defects that affect the IL-12 and IFN-gamma pathways. These cytokines are critical to control mycobacterial infections, and disruption of these pathways may lead to severe infections in otherwise healthy individuals.

IFN‑γ enhances MHC expression on antigen-presenting cells including epithelial, endothelial and connective tissue cell and monocytes cell lines. It also has weak antiviral activity and acts as a macrophage-activating factor (MAF) for tumor cytotoxicity leading to anti-tumor effects.

Recombinant anti-Human IFN gamma (Interferon gamma) antibody. Clone AF2. Engineered into new species and isotypes to improve your experiments.

The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties.

Underscoring the requirement for IFN-γ in eliminating tumors, many studies have utilized various genetic and antibody blocking approaches to demonstrate both the direct [72, 73] and indirect [74] aspects of IFN-γ-mediated tumor suppression.

2022年5月30日 · IFN-γ is a multi-effect cytokine that plays a huge role in the congenital and adaptive immune reactions. As such, the monitoring and detection of IFN-γ is very important in clinical research.

2022年5月9日 · Anti-interferon gamma autoantibodies (anti-IFN-γ autoAbs) neutralize the IFN-γ-mediated functions, contributing to immunodeficiency. A particular autoAb in patient serum had been previously...

Interferons (IFNs) are crucial cytokines in immune responses against viral and bacterial challenges. There are two main types: Type I (IFN-alpha and IFN-beta) and Type II (IFN-gamma), each with unique roles and receptor interactions. IFN-gamma, a Type II interferon, is pivotal in innate and adaptive immunity, produced mainly by T cells and NK ...

Anti-interferon (IFN)-γ autoantibodies (AIGAs) were first identified in patients with severe mycobacterial infections, and were considered to be an autoimmune phenocopy of inborn genetic errors of the IL-12/IFN-γ axis.

In 1983, a small protein and presumptive antiviral “interferon,” IFN-γ, was characterized as a factor released by antigen-stimulated lymphocytes that equips macrophages to kill intracellular bacteria, protozoa, and fungi.

2025年2月21日 · However, its immunopathogenesis remains unclear. Interferon-gamma (IFN-gamma) is a crucial cytokine that influences parasite clearance and mediates pathogenesis in experimental models of malaria.