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ICH's mission is to achieve greater harmonisation worldwide to ensure that safe, effective and high quality medicines are developed, and registered and maintained in the most resource efficient manner whilst meeting high standards.

Chi (/ kaɪ / ⓘ KY, also / xiː / HEE; [1][2] uppercase Χ, lowercase χ; Greek: χῖ) is the twenty-second letter of the Greek alphabet. Its value in Ancient Greek was an aspirated velar stop /kʰ/ (in the Western Greek alphabet: /ks/). In Koine Greek and later dialects it became a fricative ([x] / [ç]) along with Θ and Φ.

Modern English is written with a Latin-script alphabet consisting of 26 letters, with each having both uppercase and lowercase forms. The word alphabet is a compound of alpha and beta, the names of the first two letters in the Greek alphabet. Old English was first written down using the Latin alphabet during the 7th century.

In Modern Greek, the voiceless velar fricative (with its allophone, the voiceless palatal fricative [ç], occurring before front vowels) originated from the Ancient Greek voiceless aspirated stop /kʰ/ in a sound change that lenited Greek aspirated stops into fricatives. Allophone of /h/. See Albanian phonology. 'green' (f.)

Two letters, “A” and “I,” also constitute words. Until fairly recently (until 1835), the 27th letter of the alphabet (right after "z") was the ampersand (&). The English Alphabet is based on the Latin …

KH、Kh、kh 或 kH 是一个二合字母，可以指： 清軟腭塞音的送氣音，国际音标中的符号为 /kʰ/ 。 [1] [2] 在臺羅及白話字中，代表清軟腭塞音 送氣音 /kʰ/ ，如khí。 氫化鉀的化學式，寫作KH。 KH是柬埔寨官方語言高棉語的簡稱。

6 天之前 · Subsequent to α-C–H addition, the H atom of the β-agostic C–H bond is transferred directly to the hydride ligand of (iPr PCP)IrH + to give a dihydrogen ligand. The overall processes, C–H addition and β-H-transfer to hydride, are calculated to generally have minima on the IRC surface although not necessarily on the enthalpy or free ...

5 天之前 · Here, we report that enones can serve as diverse alkylidene sources for catalyst-controlled selective C–H alkylation and/or alkylidenation of various nucleophiles. Treatment of a mixture of ketone (or lactam), enone and diarylmethanol with a catalytic amount of Y[N(TMS)2]3, gave the corresponding α-C–H bond alkylation products derived from ...

2025年3月5日 · The C.I.A. director, John Ratcliffe, and the national security adviser, Michael Waltz, both confirmed the pause in intelligence support but suggested it could be short-lived if Ukraine quickly ...