HMGCS1 Gene - GeneCards | HMCS1 Protein | HMCS1 Antibody
2024年12月25日 · HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1) is a Protein Coding gene. Diseases associated with HMGCS1 include Congenital Myopathy 3 With Rigid Spine …
Targeting HMGCS1 restores chemotherapy sensitivity in acute …
HMGCS1 directly catalyzes the production of HMG-CoA, the latter is further transformed to FPP, GGPP, and cholesterol by multiple catalytic reactions. HMGCS1 promotes leukemia cell …
HMGCS1 drives drug-resistance in acute myeloid leukemia …
Hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1) is a key enzyme in the mevalonate pathway of cholesterol synthesis. Dysregulation of HMGCS1 expression is a common occurrence in …
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ (human)]
HMGCS1 drives drug-resistance in acute myeloid leukemia through endoplasmic reticulum-UPR-mitochondria axis. A new genetic locus for antipsychotic-induced weight gain: A genome-wide …
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Homo …
2025年1月4日 · Title: Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction. Decreased HMGCS1 inhibits proliferation and …
Targeting HMGCS1 restores chemotherapy sensitivity in acute …
2024年7月10日 · Through clinical specimens, animal models and cell-level studies, we explored the specific mechanism of 3-hydroxy-3-methylglutaryl coenzyme A synthase 1 (HMGCS1) in …
TET2 deficiency sensitizes tumor cells to statins by reducing HMGCS1 …
2022年11月8日 · TET2 directly regulates the expression of HMG-CoA synthase (HMGCS1) by catalyzing demethylation on its promoter region, and conversely TET2 deficiency leads to …
The mevalonate precursor enzyme HMGCS1 is a novel marker and …
When detailing the mevalonate pathway in breast cancer using a single-cell qPCR, we identified the mevalonate precursor enzyme, HMGCS1, as a specific marker of CSC-enriched …
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
2025年1月4日 · The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer. Walsh CA, Akrap …
Pan‐cancer analysis reveals the oncogenic role of 3‐hydroxy‐3 ...
Emerging studies reveals that 3‐hydroxy‐3‐methylglutaryl‐CoA synthase 1 (HMGCS1) plays vital oncogenic roles in a broad spectrum of human cancers, but there is no pan‐cancer evidence …