HaCaT Keratinocytes and Primary Epidermal Keratinocytes Have …
HaCaT cells are the immortalized human keratinocytes and have been extensively used to study the epidermal homeostasis and its pathophysiology. T helper cells play a role in various chronic dermatological conditions and they can affect skin barrier homeostasis.
Cellosaurus cell line HaCaT (CVCL_0038)
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
Growth and differentiation of HaCaT keratinocytes - PubMed
This chapter describes low-calcium culture conditions for reverting HaCaT cells to the fully basal state followed by subsequent controlled differentiation using calcium induction. HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation.
HaCaT Cell Line - Exploring Skin Biology and Disease - Cytion
HaCaT cells are a spontaneously immortalized human keratinocyte cell line originating from adult skin and representing a unique evolutionary pathway. These cells possess mutations in both alleles of the p53 gene, which is typical for mutations induced by UV radiation [3,4].
HaCaT - an overview | ScienceDirect Topics
HaCaT cells are a human epidermal keratinocyte line that has been used for investigation of multistep carcinogenesis in human cells (Boukamp et al. 1988). HaCaTs retain epidermal keratins characteristic of the more differentiated cell layers of human epidermis in vivo and are useful for in vivo analysis ( Breitkreutz et al. 1991 ).
Restoration of calcium-induced differentiation potential and tight ...
HaCaT cells have been widely used as undifferentiated epidermal keratinocytes, since these non-tumorigenic cells can be readily maintained in conventional medium and partly retain epidermal differentiation potential upon stimulation with high concentration of calcium.
HaCaT cells as a model system to study primary cilia in …
Spontaneously immortalized human keratinocytes, HaCaT are a model to study the epidermal homeostasis and pathophysiology. In contrast to what has been previously described, here, we show that HaCaT can be efficiently ciliated.
HaCaT Cells as a Reliable In Vitro Differentiation Model to ... - PubMed
To standardize the in vitro studies on keratinocytes, we investigated the use of HaCaT cells, a long-lived, spontaneously immortalized human keratinocyte line which is able to differentiate in vitro, as a suitable model to follow the release of inflammatory and repair mediators in response to TNFα or IL-1β. Different treatment conditions ...
Growth and Differentiation of HaCaT Keratinocytes
Oct 24, 2013 · This chapter describes the basic methods for growth and maintenance of HaCaT cells in the basal, undifferentiated phenotype, followed by calcium induction to produce cells exhibiting a differentiated state.
Growth and Differentiation of HaCaT Keratinocytes
HaCaT cells are a spontaneously immortalized, human keratinocyte line that has been widely used for studies of skin biology and differentiation. Under typical culture conditions HaCaT cells have a partially to fully differentiated phenotype due to. … more. * Reagents occurring with supplier names are extracted and shared by CiteAb.
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