5-HT2C receptor - Wikipedia
Like all 5-HT2 receptors, it is a G protein-coupled receptor (GPCR) that is coupled to G q /G 11 and mediates excitatory neurotransmission. HTR2C denotes the human gene encoding for the …
HTR2C Gene - GeneCards | 5HT2C Protein | 5HT2C Antibody
2024年12月25日 · HTR2C (5-Hydroxytryptamine Receptor 2C) is a Protein Coding gene. Diseases associated with HTR2C include Major Depressive Disorder and Anxiety. Among its …
Human loss-of-function variants in the serotonin 2C receptor
2022年12月19日 · Using exome sequencing of 2,548 people with severe obesity and 1,117 control individuals without obesity, we identified 13 rare variants in the gene encoding 5-HT 2C …
HTR2C 5-hydroxytryptamine receptor 2C [ Homo sapiens (human) ]
2025年3月8日 · Demonstrated that a 5-HT2AR:5-HT2CR interaction occurs in cultured cells using three complementary biophysical techniques with increasing spatial resolution. Findings …
Serotonin receptor 2c-expressing cells in the ventral CA1 control ...
2018年8月13日 · Here we genetically manipulate a subset of excitatory neurons expressing the serotonin receptor 2c (Htr2c) in the ventral hippocampus.
Neural circuits expressing the serotonin 2C receptor regulate
2024年6月28日 · Here, we investigate the role of 5-HT 2C receptor (5-HT 2C R) in regulating memory. Transgenic mice expressing a humanized HTR2C mutation exhibit impaired plasticity …
UniProt
HTR2C is coupled to G (q)/G 11 G alpha proteins and activates phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate …
HTR2C 5-hydroxytryptamine receptor 2C - NIH Genetic Testing …
2024年12月10日 · Clinical resource with information about HTR2C, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, …
Central 5-HTR2C in the Control of Metabolic Homeostasis
2021年7月21日 · The 5-hydroxytryptamine 2C receptor (5-HTR2C) is a class G protein-coupled receptor (GPCR) enriched in the hypothalamus and the brain stem, where it has been shown …
Gene structure and expression of serotonin receptor HTR2C in ...
2012年4月2日 · Although HTR2C has been implicated in genetic studies of human behavioural abnormalities, many of these have focussed on using well described polymorphic markers, …