Human T- leukemia, type 2 (HTLV-2) is usually diagnosed based on blood tests that detect the virus. However, HTLV-2 is often never suspected or diagnosed since most people never develop any signs or symptoms of the infection.

2012年5月4日 · Learn about HTLV Type I and Type II, including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find.

Human T-cell leukemia virus, type 2 (HTLV-2) is a retroviral infection that affect the T cells (a type of white blood cell). Although this virus generally causes no signs or symptoms, scientists suspect that some affected people may later develop neurological problems and/or chronic lung infections.

2020年9月7日 · The epidemiology, symptoms, diagnosis and management of human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2).

2023年7月4日 · Human T Cell lymphotropic viruses (HTLV) are a family of retroviruses. Currently, four types of this virus have been identified which are known to infect humans with a pathological consequence: HTLV-1, HTLV-2, HTLV-3, and HTLV-4. These viruses are known for their oncogenic potential as well as etiology in other disease processes.

HTLV-2 is found in Native American people throughout North, Central, and South America and in West Africa. Most HTLV-2 infections in the United States and Europe occur in injection drug users, in whom the virus is spread by needle sharing and other injection practices.

HTLV-1 and HTLV-2 share broad similarities in their overall genetic organization and expression pattern, but they differ substantially in their pathogenic properties. This review outlines distinctive features of HTLV-1 and HTLV-2 that might provide clues to explain their distinct clinical outcomes.

2019年8月7日 · Shortly after the discovery of HTLV-1, human T-cell leukemia virus type 2 (HTLV-2) was isolated from a patient with hairy cell leukemia. Despite possession of similar structural features to HTLV-1, HTLV-2 has not been definitively associated with lymphoproliferative disease.

HTLV-2 was first identified from splenic tissue from a patient with hairy cell leukemia and is related to HTLV-1. Although a direct implication of the etiologic role of HTLV-2 in disease remains elusive, characteristics of HTLV-2 infection are similar in nature to those of HTLV-1. Like HTLV-1, HTLV-2 infects and transforms T lymphocytes in culture.

HTLV-2 can induce transformation of T-cells in culture, but does only very rarely induce adult T-cell leukemia (ATL) which is a malignant transformation of T-lymphocytes. May induce atypical hair-cell leukemia.