
HSPA5 Gene - GeneCards | BIP Protein | BIP Antibody
2024年12月25日 · HSPA5 (Heat Shock Protein Family A (Hsp70) Member 5) is a Protein Coding gene. Diseases associated with HSPA5 include Mucormycosis and Japanese Encephalitis. Among its related pathways are Unfolded Protein Response (UPR) and Response to elevated platelet cytosolic Ca2+.
HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
2017年4月15日 · Here, we show that heatshock 70-kDa protein 5 (HSPA5) negatively regulates ferroptosis in human pancreatic ductal adenocarcinoma (PDAC) cells. Mechanistically, activating transcription factor 4 (ATF4) resulted in the induction of HSPA5, which in turn bound glutathione peroxidase 4 (GPX4) and protected against GPX4 protein degradation and ...
HSPA5 heat shock protein family A (Hsp70) member 5 [ (human)]
HSPA5, as a ferroptosis regulator, may serve as a potential therapeutic for head and neck squamous cell carcinoma. HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Identification of heat shock protein family A member 5 (HSPA5
2023年5月8日 · Heat shock protein family A (Hsp70) member 5 (HSPA5) is an endoplasmic reticulum chaperone, which regulates cell metabolism, particularly lipid metabolism. While HSPA5’s role in regulating cell...
HSPA5 - SpringerLink
HSPA5 gene encodes heat shock protein family A member 5 protein commonly known as GRP78 (glucose-regulated protein 78) or BiP (binding immunoglobulin protein) (“GRP78” will be used to refer to the protein throughout the remainder of this text for simplicity).
New progresses on cell surface protein HSPA5/BiP/GRP78 in …
In the current study, we review the newest research progresses on cell surface protein HSPA5 expressions, functions, and mechanisms for cancers and SARS-CoV-2 invasion. The therapeutic and prognostic significances and prospects in cancers and COVID-19 disease by targeting HSPA5 are also discussed.
HSPA5 heat shock protein family A (Hsp70) member 5 [Homo …
2025年2月9日 · A stable-isotope labeling by amino acids in cell culture coupled with mass spectrometry-based proteomics identifies upregulation of heat shock 70kDa protein 5 (HSPA5, GRP78) expression by HIV-1 Vpr in Vpr transduced macrophages
Identification of heat shock protein family A member 5 (HSPA5
Heat shock protein family A (Hsp70) member 5 (HSPA5) is an endoplasmic reticulum chaperone, which regulates cell metabolism, particularly lipid metabolism. While HSPA5's role in regulating cell function is well described, HSPA5 binding to RNA …
The HSPA5 gene and its putative association with human ageing
2023年4月23日 · Elevated expression and atypical translocation of this protein to the cell surface has been reported in viral infections and some types of cancer cells. At the cell surface this protein may facilitate viral attachment and entry to host cells.
HSPA5 heat shock protein family A (Hsp70) member 5
2024年3月10日 · Identification of heat shock protein family A member 5 (HSPA5) targets involved in nonalcoholic fatty liver disease. HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer. Wang Q, Ke S, Liu Z, Shao H, He M, Guo JWang Q, et al. Int J Mol Sci, 2023 Mar 7. PMID 36982218.