Heat shock proteins: Biological functions, pathological roles, and ...
2022年8月2日 · The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect cells from stresses. HSP protein families are classified based on their molecular weights, mainly including large HSPs, HSP90 …
Heat shock proteins: a therapeutic target worth to consider
Heat shock proteins (HSPs) are the molecular chaperones, that are not only expressed during the normal growth process of cell cycle consecutively, but also get induced in cells during various stress conditions produced by cellular insult, environmental …
The HSP90 Family: Structure, Regulation, Function, and …
HSP90 proteins take part in essential cellular processes and regulatory pathways like apoptosis, cell cycle control, cell viability, protein folding and degradation, and signalling events. In addition, they induce the adaptive immunity by activation of antigen presenting cells and dendritic cells.
Heat Shock Protein - an overview | ScienceDirect Topics
Heat shock proteins (HSPs) are a diverse group of proteins that are ubiquitously expressed under normal physiological conditions to perform a range of housekeeping functions that maintain regular cell metabolism.
Heat Shock Proteins: Agents of Cancer Development and …
2021年10月25日 · Heat shock proteins (HSPs) constitute a large family of molecular chaperones classified by their molecular weights, and they include HSP27, HSP40, HSP60, HSP70, and HSP90. HSPs function in diverse physiological and protective processes to assist in maintaining cellular homeostasis.
Heat-shock proteins: chaperoning DNA repair | Oncogene
2019年9月20日 · HSPs (heat-shock proteins) constitute the first line of protection for cells exposed to stressful conditions. They participate to the safeguard of cell integrity, keeping functional signaling...
The Hsp70 chaperone network | Nature Reviews Molecular Cell …
2019年6月28日 · In this Review we describe recent advances that have increased our understanding of the molecular mechanisms and working principles of the Hsp70 network.
Roles of heat-shock proteins in innate and adaptive immunity
2002年3月1日 · Heat-shock proteins (HSPs) are the most abundant and ubiquitous soluble intracellular proteins. In single-cell organisms, invertebrates and vertebrates, they perform a multitude of...
Heat Shock Protein - an overview | ScienceDirect Topics
Heat shock proteins are a class of highly conserved proteins involved in a wide range of stress and stimuli, specially expressed following IRI [50, 97].
Small heat shock proteins: Role in cellular functions and pathology
2015年4月1日 · Organisms and cells respond to various stress conditions such as environmental, metabolic or pathophysiological stress by selectively up-regulating the expression of a group of proteins called the heat shock proteins (Hsps).
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