Reversible phase separation of HSF1 is required for an acute ...
2022年3月7日 · Heat-shock transcription factor 1 (HSF1) orchestrates the fast and vast cellular response to heat shock through increased expression of heat-shock proteins. However, how …
HSF1 at a glance - PubMed
2014年1月15日 · Heat shock factor 1 (HSF1) is an evolutionarily highly conserved transcription factor that coordinates stress-induced transcription and directs versatile physiological …
HSF1 Gene - GeneCards | HSF1 Protein | HSF1 Antibody
2024年12月25日 · Complete information for HSF1 gene (Protein Coding), Heat Shock Transcription Factor 1, including: function, proteins, disorders, pathways, orthologs, and …
Molecular mechanisms of heat shock factor 1 regulation
2022年3月1日 · In this review, we discuss the regulation of Hsf1’s transcriptional activity by multiple layers of control circuits involving Hsf1 synthesis and degradation, conformational …
HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor …
HSF1 (heat shock factor 1) is an evolutionarily conserved master transcriptional regulator of the heat shock response (HSR) in eukaryotic cells. In response to high temperatures, HSF1 …
The stress response regulator HSF1 modulates natural killer cell …
2024年9月2日 · Here, we leverage an in vivo model of HSF1 activation and single-cell transcriptomic tumour profiling to show that augmented HSF1 activity in natural killer (NK) cells …
The molecular mechanism of temperature-dependent phase …
2025年1月10日 · Heat shock factor 1 (HSF1) is the critical orchestrator of cell responses to heat shock, and its dysfunction is linked to various diseases. HSF1 undergoes phase separation …
HSF1 at a glance | Journal of Cell Science - The Company of …
2014年1月15日 · Heat shock factor 1 (HSF1) is an evolutionarily highly conserved transcription factor that coordinates stress-induced transcription and directs versatile physiological …
HSF1 heat shock transcription factor 1 [ (human)] - National …
HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia. Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer. HSF1 …
HSF1 as a Cancer Biomarker and Therapeutic Target - PMC
HSF1 is a helix-turn-helix transcription factor that binds to heat shock elements (HSEs) located in the promoters of target genes [4–7]. HSF1 is now increasingly being recognized to play a role …
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