HOXA10 Gene - GeneCards | HXA10 Protein | HXA10 Antibody
Dec 25, 2024 · HOXA10 (Homeobox A10) is a Protein Coding gene. Diseases associated with HOXA10 include 17 Alpha-Hydroxylase/17,20-Lyase Deficiency and Leukemia, Acute Lymphoblastic. Among its related pathways is Signaling events mediated by HDAC Class III.
Role of HOXA10 in pathologies of the endometrium
Nov 5, 2024 · HOXA10 has a key role in endometrial receptivity, embryo implantation, and decidua functions; its dysregulation is associated with a variety of endometrial pathologies. Graphical Abstract. Homeobox (Hox) genes are evolutionarily conserved developmental transcription factors.
HOXA10 mediates epithelial-mesenchymal transition to promote …
Feb 9, 2021 · In this study, we demonstrated HOXA10 was upregulated in GC patients and the difference was even more pronounced in patients with lymph node metastasis (LNM) than without. Functionally, HOXA10 promoted migration and invasion of GC cells in vitro and accelerated lung metastasis in vivo.
The roles and expression of HOXA/Hoxa10 gene: A
Jun 1, 2022 · In particular, the HOXA / Hoxa10 gene is an intrinsic component of implantation, decidualization, and immunomodulation in the adult uterus. It was, therefore, suggested that knowledge of HOXA / Hoxa10 regulation might be essential in navigating molecular mechanisms with the aim of enhancing female reproductive potential.
3206 - Gene ResultHOXA10 homeobox A10 [ (human)] - National …
HOXA10 Regulates the Synthesis of Cholesterol in Endometrial Stromal Cells. HOXA10 improves endometrial receptivity by upregulating E-cadherindagger. Comprehensive Landscape of HOXA2, HOXA9, and HOXA10 as Potential Biomarkers for Predicting Progression and Prognosis in Prostate Cancer.
HOXA10 homeobox A10 [Homo sapiens (human)] - Gene - NCBI
Title: A Novel HOXA10-Associated 5-Gene-Based Prognostic Signature for Stratification of Short-term Survivors of Pancreatic Ductal Adenocarcinoma. Expression of HOXA10 Gene in Women with Endometriosis: A Systematic Review.
HoxA10 Protein Regulates Transcription of Gene Encoding Fibroblast ...
May 25, 2012 · HoxA10 is a highly conserved homeodomain transcription factor that plays key roles in embryogenesis and definitive hematopoiesis. HOX genes are clustered in four groups (A–D) on four chromosomes in mouse and man (1).
HOX基因及其辅因子家族调控胚胎着床的分子机制_百度百科
同源框基因HOXA10是目前公认的胚胎着床标志性基因和着床相关分子网络中的重要节点。本项目组以HOXA-10为主线，对39种HOX家族基因进行Affymetrix筛选，发现除HOXA10外，HOXA9、HOXA11、HOXB6、HOXD10也在女性生殖系统中呈现高表达。
Role of HOXA10 in pathologies of the endometrium - PubMed
Nov 5, 2024 · HOXA10 belongs to the homeobox gene family and is essential for uterine biogenesis, endometrial receptivity, embryo implantation, and stromal cell decidualization. Available evidence suggests that the expression of HOXA10 is dysregulated in different endometrial disorders like endometrial hyperplasi …
子宫内膜腺癌分化的新机制：同源盒基因HOXA10的功能研究
课题组拟从分子、细胞、组织、动物实验等多个层面，以HOXA10-WNT信号通路-子宫内膜腺癌分化这个新视角，以期阐明HOXA10基因调控子宫内膜腺癌分化的分子机制，为子宫内膜癌分子靶向治疗提供潜在新靶标。 子宫内膜腺癌的发生及分化分子机制尚不清楚。 同源盒基因编码一簇保守的转录因子家族，参与调控胚胎发育，器官形成和肿瘤发生。 我们既往研究发现HOXA10基因表达水平的高低与肿瘤分化级别成正相关，增强HOXA10基因在低分化子宫内膜腺癌细胞中表达并 …