Supplementary test information for Antinuclear Antibody (ANA) With HEp-2 Substrate such as test interpretation, additional tests to consider, and other technical data.

Autoantibodies targeting antigens in the nuclear region in the HEp-2 cell line substrate using the indirect immunofluorescence assay (IFA) have traditionally been called antinuclear antibody …

Antinuclear antibodies (ANAs, also known as antinuclear factor or ANF) [2] are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the immune system produces …

Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for discriminating antinuclear antibody-positive healthy individuals and patients with autoimmune rheumatic diseases …

2022年4月25日 · Your blood sample is mixed with human cells (usually HEp-2 cells) fixed on a slide. If ANAs are present in your blood, they will bind to the nuclei of these cells. A fluorescent …

The indirect immunofluorescence assay (IIFA) on HEp-2 cells is widely used for detection of antinuclear antibodies (ANA). The dichotomous outcome, negative or positive, is integrated in …

Antinuclear antibody (ANA) testing is used in the diagnostic evaluation of various autoimmune diseases, including connective tissue diseases such as systemic lupus erythematosus (SLE), …

The HEp-2 cell line contains HeLa marker chromosomes and were derived via HeLa contamination. This line was originally thought to be derived from an epidermoid carcinoma of …

2018年4月29日 · HEp-2 cell line offers the possibility for detection of more than hundred different autoantibodies to nuclear and cytoplasmic autoantigens. The effects of ANA detection with …

Hep-2/Hep2 cells are invaluable for researchers engaged in the analysis of autoantibodies, and they are currently one of the most common substrates for antinuclear antibody detection by …