293 [HEK-293] - CRL-1573 - ATCC
293 [HEK-293] is a cell line exhibiting epithelial morphology that was isolated from the kidney of a human embryo. This cell line can be used in industrial biotechnology and toxicology research. It has applications in efficacy testing and viruscide testing.
HEK293 Cells: Background, Applications, Protocols, and More
HEK293 cells are immortalized human embryonic kidney cells and are among the most commonly used cell lines in research. HEK293 is a robust, fast-growing, and low-maintenance cell line with a variety of applications, including receptor signaling, cancer research, protein production, and CRISPR gene editing.
HEK293 Cell Line: A Cornerstone in Modern Cellular Research
HEK293 cells are a human embryonic kidney cell line derived from the kidney tissue of an electively terminated human embryo of unknown parenthood. The cells were established by a Dutch biologist named Alex Van der Eb in the early 1970s.
HEK293 Cells - A Guide to This Incredibly Useful Cell Line
Feb 6, 2023 · HEK293 cells are one of the most commonly used cell lines. But what are they? Why should you use them? And what does the ‘293’ mean?
HEK293 Cell Line - an overview | ScienceDirect Topics
The HEK293 cell line, derived from human embryonic kidney cells by transformation with sheared adenovirus type 5 DNA (Graham et al., 1977), is widely employed as an alternative to Xenopus oocytes for the heterologous expression of a variety of proteins, including mammalian voltage-gated sodium channels (Thomas and Smart, 2005).
Evolution from adherent to suspension: systems biology of HEK293 cell …
Nov 4, 2020 · Here we present a genomic, transcriptomic and metabolic gene analysis of six of the most widely used HEK293 cell lines. Changes in gene copy and expression between industrial progeny cell...
Human Embryonic Kidney 293 Cells: A Vehicle for ... - PubMed
In this article, we review the literature on HEK293 cells regarding their origins but also stress their advancements into the different cell lines engineered and discuss some significant aspects which make them versatile systems for biopharmaceutical manufacturing, drug screening, structural biology research, and electrophysiology applications.
HEK 293 Cells: Background, Advantages and Applications
Jun 18, 2021 · HEK 293 cells are hypotriploid human cell lines. They carry 64 chromosomes, three X chromosome copies, and an incorporation of 4 kbp Ad5 to chromosome 19 of the HEK 293 genome indicating cytogenetic instability.
Genome dynamics of the human embryonic kidney 293 lineage …
Sep 3, 2014 · The human embryonic kidney (HEK) 293 cell line and its derivatives are used in experiments ranging from signal transduction and protein interaction studies over viral packaging to rapid...
HEK293 in cell biology and cancer research: phenotype ... - PubMed
Sep 15, 2015 · 293 cell line (widely known as the Human Embryonic Kidney 293 cells) and its derivatives were the most used cells after HeLa in cell biology studies and after CHO in biotechnology as a vehicle for the production of adenoviral vaccines and recombinant proteins, for analysis of the neuronal synapse fo …
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