
HEK 293 cells - Wikipedia
Human embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, are an immortalised cell line derived from HEK cells isolated from a female fetus in the 1970s. [1][2] The HEK 293 cell line has been widely used in research for decades due to its reliable and fast growth and propensity for transfection.
293 [HEK-293] - CRL-1573 - ATCC
Stauderman KA, et al. Characterization of human recombinant neuronal nicotinic acetylcholine receptor subunit combinations alpha 2 beta 4, alpha 3 beta 4 and alpha 4 beta 4 stably expressed in HEK293 cells. J. Pharmacol. Exp. Ther. 284: 777-789, 1998. PubMed: 9454827
HEK293 Cell Line as a Platform to Produce Recombinant Proteins …
The human cell line, HEK293, have emerged to be the main production platform for therapeutic viral vectors. Advancements in cell line developments would see more HEK293 clones or derivatives developed for growth in a serum-free suspension …
A Deep Dive into the HEK293 Cell Line Family
2024年11月12日 · There are several derived sublines of hek293 cells, each with distinct characteristics and applications. Pricella introduces the key features and uses of four major hek293 subtypes: 293T, 293F, 293H, and 293S.
HEK293 Cells - A Guide to This Incredibly Useful Cell Line
2023年2月6日 · HEK293 cells are Human Embryonic Kidney cells, originally isolated and grown by Dutch biologist Alex Van der Eb in the early 1970s. They were transfected with sheared adenovirus 5 (Ad5) DNA by Frank Graham, a postdoc in Van der Eb’s lab.
Morphology of HEK293 Cells | Thermo Fisher Scientific - US
The HEK293 cell line is a permanent line established from primary embryonic human kidney, which was transformed with sheared human adenovirus type 5 DNA. The adenoviral genes expressed in this cell line allow the cells to produce very high levels of recombinant proteins.
Affecting HEK293 Cell Growth and Production Performance by Modifying ...
The HEK293 cell line has earned its place as a producer of biotherapeutics. In addition to its ease of growth in serum-free suspension culture and its amenability to transfection, this cell line’s most important attribute is its human origin, which ...
HEK 293 Cells: Background, Advantages and Applications
2021年6月18日 · Human Embryonic Kidney 293 (HEK 293) cells are one of the most frequently used cell lines for biotechnology and research studies. These cells are quite popular because of their distinct properties like fast-growing, robustness, and ease of maintenance and transfection.
Evolution from adherent to suspension: systems biology of HEK293 …
Here we present a genomic, transcriptomic and metabolic gene analysis of six of the most widely used HEK293 cell lines. Changes in gene copy and expression between industrial progeny cell lines and the original HEK293 were associated with cellular component organization, cell motility and cell adhesion.
HEK 293 cell lines - Washington State University
HEK 293 cell lines are commonly used in cancer research. Biosafety Level 2 (BSL-2) protections apply to work with pathogens or infectious organisms associated with human diseases. These organisms pose a moderate health hazard.