2024年12月25日 · HDAC9 (Histone Deacetylase 9) is a Protein Coding gene. Diseases associated with HDAC9 include Auriculocondylar Syndrome 4 and Primary Cutaneous T-Cell …

2020年8月27日 · HDAC9 (histone deacetylase 9) actions in atherosclerosis. HDAC9 risk alleles can increase HDAC9 expression. HDAC9 interacts with IKKs (inhibitory kappa B kinases), …

As a member of the class IIa histone deacetylases (HDACs), HDAC9 catalyzes the deacetylation of histones and transcription factors, commonly leading to the suppression of gene …

This review summarizes the most recent discoveries regarding HDAC9 as a crucial regulator of specific physiological systems and, more importantly, highlights the diverse spectrum of …

2023年5月25日 · Here, the authors show that HDAC9 is upregulated in the fibrotic kidney and promotes epithelial cell cycle arrest in G2/M by regulating STAT1.

2019年8月26日 · Our findings suggest that the development of HDAC9-selective HDACis is a potential approach to improve the efficacy of chemotherapy and reduce systemic toxicity.

CircHDAC9 regulates myocardial ischemia-reperfusion injury via miR-671-5p/SOX4 signaling axis. Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment …

HDAC9 deletion or pharmacological inhibition by TMP195 inhibits such inflammatory phenotypes and ameliorates atherosclerosis and enhances plaque stability in mice. Certain HDAC …

4 天之前 · HDAC9, encoding the signal-responsive histone deacetylase 9 (HDAC9), is a major risk locus for myocardial infarction, stroke, and other vascular disorders.In mouse models of …

2025年1月28日 · Common genetic variants in a cis-regulatory element at HDAC9, which regulates expression of the histone deacetylase HDAC9, are a major risk factor for cardiovascular disease.