HCT 116 - CCL-247 - ATCC
HCT 116 cell line was isolated from the colon of an adult male with colon cancer. It has a mutation in codon 13 of the ras proto-oncogene and can be used as a positive control for PCR assays of mutation in this codon.
HCT116 cells - Wikipedia
HCT116 cells are used in a variety of biomedical studies involving colon cancer proliferation and corresponding inhibitors. The cell line has been used in tumorigenicity studies, along with other research that has shown that Cyclin D1 holds large importance for the activity of
HCT 116 - 维基百科，自由的百科全书
染色後的hct116細胞顯示出 h2afx基因 （ 英语 ： h2afx ） （綠色部分）和端粒狀dna（紅色部分） HCT 116 是用於研究治療方案及進行 藥物篩選 的 人類 結腸癌 細胞系 [ 1 ] 。
HCT116 Cell Line: A Pillar in Colorectal Cancer Research
HCT116 Cell Line: A Pillar in Colorectal Cancer Research. The HCT116 cell line serves as a cornerstone in the exploration of colorectal cancer, offering invaluable insights into the disease's pathogenesis and potential therapeutic avenues. Renowned for its utility in cancer research and pharmacological assessments, HCT116 facilitates pivotal ...
Cellosaurus cell line HCT 116 (CVCL_0291)
Isolation and characterization of two novel colorectal cancer cell lines, containing a subpopulation with potential stem-like properties: treatment options by MYC/NMYC inhibition. Cancers (Basel) 12:2582.1-2582.34(2020)
In Silico HCT116 Human Colon Cancer Cell-Based Models En …
To discover new inhibitors against the human colon carcinoma HCT116 cell line, two quantitative structure–activity relationship (QSAR) studies using molecular and nuclear magnetic resonance (NMR) descriptors were developed through exploration of machine learning techniques and using the value of half maximal inhibitory concentration (IC 50 ...
Cell Culture Protocol for HCT 116 cells HCT 116 (ATCC number CCL-247): colorectal carcinoma cell line Growth medium: McCoy’s 5a Medium (GIBCO # 16600) + 10% FBS + 100 units/ml penicillin + 100 μg/ml streptomycin (GIBCO # 15140-122). Protocol: 1. Take out the HCT 116 stock vial from liquid nitrogen (we freeze at 5x106 cells per vial) and
β-catenin activation down-regulates cell-cell junction-related …
Dec 5, 2019 · We utilized three HCT116 cell lines with differential β-catenin mutation status: parental HCT116 (HCT116-P) cells harboring one WT and one mutant allele (Ser45 del), HCT116-WT cells...
Characterization of HCT116 Human Colon Cancer Cells in an …
Jun 15, 2008 · The HCT116 human colon cancer cell line in this in vivo model system provides a tool to dissect the molecular mechanisms involved in the metastatic cascade. Further knowledge of invasion and successful growth of tumor cells at distant sites may allow for the development of novel therapeutic agents to impact the morbidity and mortality ...
Development and molecular characterization of HCT-116 cell lines ...
Dec 1, 2002 · Three independent cell lines derived from the colonic epithelial cell line HCT-116 were selected for resistance to bile salt-induced apoptosis. These cell lines were developed as tissue culture models of apoptosis resistance.