HCT 116 is an adherent cell line isolated from the colon of a patient with colon cancer. It has a mutation in codon 13 of the ras-proto-oncogene. This cell line is near-diploid and has a …

Understanding the roots and basic traits of HCT116 cells, such as their morphological features, genetic makeup, and cellular dimensions, is essential for researchers embarking on studies …

Part of: NCI-60 cancer cell line panel. Population: Caucasian. Doubling time: 17.1 hours (PubMed= 22628656); 22 hours (PubMed= 23546019); 25.02 hours (PubMed= 25944804); 36 …

2008年6月15日 · HCT116 human colon cancer cell line in this in vivo model system provides a tool to dissect the molecular mechanism involved in the metastatic cascade. This orthotopic …

HCT116 (ATCC® CCL-247 ™) is a human colorectal carcinoma cell line initiated from an adult male. The cells are adherent with an epithelial morphology. Following implantation into …

2019年12月5日 · We investigated β-catenin localization, transcriptome, and phenotypic differences of HCT116 cells containing a wild-type (HCT116-WT) or mutant β-catenin allele …

Here, we report the building of two QSAR studies using molecular and NMR descriptors for the prediction of anticancer activity against the human colon carcinoma HCT116 cell line, using …

The HCT116 and NCM460 data for 24 h and 48 h were analyzed by two-way analysis of variance with cell type (HCT116 or NCM460), treatment concentration, and their interaction as fixed …

HCT116 cells upregulated AKT, MAPK and PLC signaling under GFDS conditions to counter stress. In contrast, HCT116b cells downregulated these signaling molecules by …

The HCT116 VIM RFP reporter cell line carries a knock-in red fluorescent protein (RFP) reporter, which was integrated before the stop codon at the last exon of the endogenous vimentin (VIM) …