H3K4me3 - Wikipedia
H3K4me3 is used as a histone code or histone mark in epigenetic studies (usually identified through chromatin immunoprecipitation) to identify active gene promoters. H3K4me3 promotes …
组蛋白修饰 | 一文带你了解H3K4me3 - 知乎 - 知乎专栏
H3K4me3是组蛋白H3第四位赖氨酸在甲基转移酶 (HMT) 催化下发生三甲基化。 H3K4me3是最重要的甲基化修饰之一，真核生物中该修饰在转录起始位点普遍发生，通常在基因的启动子附近 …
H3K4甲基化（H3K4me3）在生物学和疾病中的作用 - 简书
Jan 3, 2025 · 三甲基化的H3赖氨酸4（H3K4me3）是最受研究的组蛋白修饰之一，因为它在转录起始位点的富集以及与基因表达和决定细胞命运、发育和疾病的过程相关。 在这篇综述中，我 …
H3K4me3 - 百度百科
H3K4me3，中文名组蛋白第三亚基四号赖氨酸的三甲基化，H3K4me3是指组蛋白第三亚基四号赖氨酸的三甲基化；一个特定的组蛋白赖氨酸甲基转移酶 ( HMT )，将三甲基团转移到组蛋白 3 …
国自然热点 | “增强子”的重要标记——H3K4me1 - 知乎
Sep 23, 2023 · 研究表明，H3K4me3主要富集在转录起始位点附近的启动子区域，而大多数H3K4me1修饰富集在增强子区域。 识别H3K4me1富集区和H3K4me3贫乏区，或者H3K4me1 …
H3K4 methylation at active genes mitigates transcription ... - Nature
Feb 10, 2020 · Transcription-deposited H3K4 methylation (H3K4me) is associated with regions that are susceptible to TRCs; however, the interplay between H3K4me and TRCs is unknown. …
Roles of H3K4 methylation in biology and disease - ScienceDirect
Feb 1, 2025 · Trimethylated H3 lysine 4 (H3K4me3) is one of the most studied histone modifications owing to its enrichment at the start sites of transcription and its association with …
Nature：揭示H3K4me3在转录调控中的具体作用 - 知乎
2023年3月1日，美国纪念斯隆-凯瑟琳癌症中心 Kristian Helin 研究组在 Nature 发表了题为：H3K4me3 regulates RNA polymerase II promoter-proximal pause-release 的研究长文，对这 …
Functional Roles of H3K4 Methylation in Transcriptional Regulation
Histone 3 lysine 4 methylation (H3K4me) is a highly evolutionary conserved chromatin modification associated with active transcription, and its three methylation states-mono, di, and …
Cell Research｜陈飞团队揭示出H3K4me2/3直接调控基因转录的机制
Mar 17, 2023 · 2023年3月15日，复旦大学生物医学研究院 陈飞 团队在 Cell Research 上发表了题为 H3K4me2/3 modulate the stability of RNA polymerase II pausing 的研究论文，回答了困扰 …