Gummas are most commonly found in the liver (gumma hepatis), but can also be found in brain, heart, skin, bone, testis, and other tissues, leading to a variety of potential problems including neurological disorders or heart valve disease.

2019年12月11日 · These findings are diagnostic of syphilis. A 28 year old man presents with fever, sore throat, lymphadenopathy and a skin rash. Which of the following is the most important cutaneous finding that should prompt suspicion of syphilis?

These sites are termed “gumma” and present as ulcerated, nodular, or firm lesions that may cause significant destruction of the tissues. When gummas are found inside the mouth, the most common location is the tongue or palate.

Syphilis is spread by infection with the bacteria through direct skin-to-skin contact with a chancre sore. A gumma is a tumor-like growth associated with syphilis. [3] . Continue to learn about the different stages of syphilis, the gumma of syphilis, and treatment for gummas.

Syphilis is an infectious disease caused by the spirochaete Treponema pallidum. Primary syphilis (primary chancre) demonstrates an acanthotic epidermis which erodes with time to become ulcerated. Under the ulcer bed there is typically a dense lymphocytic response, numerous plasma cells, and endothelial swelling (figure 1).

Gummas are most commonly found in the liver (gumma hepatis), but can also be found in brain, heart, skin, bone, testis, and other tissues, leading to a variety of potential problems including neurological disorders or heart valve disease.

Although cerebral syphilitic gumma is not confirmed by pathology, it can be diagnosed by clinical and laboratory examinations. Syphilitic gumma also shows a unique meningeal tail sign of meningiomas, indicating that cerebral syphilitic gumma is reversible.