GSPT1 Gene - GeneCards | ERF3A Protein | ERF3A Antibody
Dec 25, 2024 · GSPT1 (G1 To S Phase Transition 1) is a Protein Coding gene. Diseases associated with GSPT1 include Duane-Radial Ray Syndrome and Myelodysplastic Syndrome . …
Merging PROTAC and molecular glue for degrading BTK and GSPT1 …
Aug 20, 2021 · GSPT1 (G1 to S phase transition 1) is a translation termination factor that recognizes the termination codon by binding eRF1, forcing the proteins to dissociate from the …
Molecular glues targeting GSPT1 in cancers: A potent therapy
Feb 1, 2024 · Molecular glue targeting GSPT1 is an innovative antitumor agent, which induces degradation of GSPT1 and affects proliferation, migration, and invasion of various tumor cells. …
Molecular glues targeting GSPT1 in cancers: A potent therapy
This review aims to introduce current understanding of antitumor mechanism of molecular glues targeting GSPT1, summarize pharmacology profiles of existing molecular glues, and outline …
Development and therapeutic potential of GSPT1 molecular glue …
Studied demonstrated that GSPT1 plays a vital role in the acute myeloid leukemia (AML) and MYC-driven lung cancer. Thus, molecular glue (MG) degraders targeting GSPT1 is a novel …
Potential of GSPT1 as a novel target for glioblastoma therapy
Aug 8, 2024 · We previously reported that G1 to S phase transition 1 (GSPT1) depletion induces delayed cell cycle in primary astrocytes. Herein, we examined the potential of GSPT1 as a …
GSPT1 G1 to S phase transition 1 [ (human)] - National Center for ...
Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3beta/CyclinD1 pathway. miR-27b-3p suppresses gastric cancer cell …
Degradation of GSPT1 causes TP53-independent cell death in …
Aug 15, 2022 · We identified the domains of GSPT1 essential for cell survival and show that GSPT1 degradation leads to impaired translation termination, activation of the integrated …
Degradation of GSPT1 causes TP53-independent cell death in …
We identified the domains of GSPT1 essential for cell survival and show that GSPT1 degradation leads to impaired translation termination, activation of the integrated stress response pathway, …
GSPT1 G1 to S phase transition 1 [ Homo sapiens (human) ]
Feb 9, 2025 · Title: Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway. miR-27b-3p suppresses …
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