
The role of S-nitrosoglutathione reductase (GSNOR) in human ... - PubMed
GSNOR modulates reactive nitric oxide (•NO) availability in the cell by catalyzing the breakdown of GSNO, and indirectly regulates S-nitrosothiols (RSNOs) through GSNO-mediated protein S …
S-Nitrosoglutathione - Wikipedia
S-Nitrosoglutathione (GSNO) is an endogenous S -nitrosothiol (SNO) that plays a critical role in nitric oxide (NO) signaling and is a source of bioavailable NO. NO coexists in cells with SNOs …
亚硝基化谷胱甘肽还原酶(GSNOR): 一个调控炎症反应的新分子
炎症因子的表达调控是炎症反应的关键步骤,与自身免疫疾病以及癌症等密切相关.一氧化氮 (nitric oxide,NO)在炎症因子表达调控中具有重要作用,但已有的研究多关注于NO合成对炎症 …
Circ Res 季勇团队首次发现GSNOR的线粒体定位并揭示线粒体GSNOR …
该研究发现了心肌肥厚中调控MLP巯基亚硝基化修饰的酶是谷胱甘肽还原酶(S-nitrosoglutathione reductase, GSNOR)。 GSNOR是一种去巯基亚硝基化修饰蛋白,在心肌肥厚时,其表达降低促 …
S-Nitrosoglutathione Reductase (GSNOR) – Vierling Lab - UMass
We are studying the enzyme S-nitrosoglutathione reductase (GSNOR), originally identified in plants and other organisms as formaldehyde dehydrogenase (FALDH), a type III alcohol …
季勇教授团队揭示线粒体GSNOR在心力衰竭中的重要保护作用
Jul 5, 2023 · 该论文首次发现GSNOR在心肌细胞线粒体定位,并明确线粒体GSNOR(谷胱甘肽还原酶,S-nitrosoglutathione reductase)通过调控线粒体蛋白ANT1(腺嘌呤核苷酸转位 …
The Emerging Role of GSNOR in Oxidative Stress Regulation
Feb 1, 2021 · In this review, we focus on the emerging role of GSNOR as a master regulator in oxidative stress through its regulation of the interaction of ROS, RNS, and Fe, and highlight …
S-亚硝基谷胱甘肽还原酶 (GSNOR) 在人类疾病和治疗中的作用 …
GSNOR modulates reactive nitric oxide (•NO) availability in the cell by catalyzing the breakdown of GSNO, and indirectly regulates S-nitrosothiols (RSNOs) through GSNO-mediated protein S …
GSNOR negatively regulates the NLRP3 inflammasome via
Apr 3, 2024 · Our findings suggested that GSNOR is a regulator of the NLRP3 inflammasome and that reducing the level of S -nitrosylated MAPK14 may constitute an effective strategy for …
姚永刚课题组发现S-亚硝基化谷胱甘肽还原酶(GSNOR)调控MPT…
Aug 11, 2022 · S-亚硝基谷胱甘肽还原酶(GSNOR)由ADH5基因编码,是乙醇脱氢酶(ADH)家族中的成员。前人研究发现,生物体内的GSNOR能调控多种蛋白的S-亚硝基化,参与多种生 …