
Anti-glutamate receptor antibodies - Wikipedia
Anti- glutamate receptor antibodies are autoantibodies detected in serum and/or cerebrospinal fluid samples of a variety of disorders such as encephalitis, epilepsy and ataxia.
Metabotropic glutamate receptor 3 - Wikipedia
Metabotropic glutamate receptor 3 (mGluR3) is an inhibitory G i /G 0 -coupled G-protein coupled receptor (GPCR) [4] generally localized to presynaptic sites of neurons in classical circuits. [5] .
GRIA3 - Wikipedia
GluR3 is a gene product of the GRIA3 gene and its pre-mRNA is subject to RNA editing. A to I RNA editing is catalyzed by a family of adenosine deaminases acting on RNA (ADARs) that specifically recognize adenosines within double-stranded regions of pre-mRNAs and deaminate them to inosine.
GluR3 Monoclonal Antibody (3B3) (32-0400) - Thermo Fisher Scientific
Invitrogen Anti-GluR3 Monoclonal (3B3), Catalog # 32-0400. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human, Non-human primate, Rat samples. Supplied as 100 µg purified antibody (0.5 mg/mL).
GRIA3 Gene - GeneCards | GRIA3 Protein | GRIA3 Antibody
2024年12月25日 · GRIA3 (Glutamate Ionotropic Receptor AMPA Type Subunit 3) is a Protein Coding gene. Diseases associated with GRIA3 include Intellectual Developmental Disorder, X-Linked, Syndromic, Wu Type and Syndromic X-Linked Intellectual Disability 94. Among its related pathways are Trafficking of AMPA receptors and Transmission across Chemical Synapses.
Human T Cells Express a Functional Ionotropic Glutamate Receptor GluR3 …
2003年4月15日 · We discovered that normal human T cells, human T leukemia cells, and mouse anti-myelin basic protein T cells express high levels of glutamate ion channel receptor (ionotropic) of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) subtype 3 (GluR3).
TCR Activation Eliminates Glutamate Receptor GluR3 from the Cell ...
2007年1月15日 · In this study, we found by GluR3-specific immunostaining, flow cytometry, and Western blots that GluR3 cell surface expression decreases dramatically following TCR activation of human T cells. CXCR4, VLA-4, and VLA-6 also decrease substantially, whereas CD147 increases as expected, after TCR activation.
GLUTAMATE RECEPTOR ANTIBODIES IN NEUROLOGICAL DISEASES: Anti-AMPA-GluR3 ...
2014年8月1日 · Anti-AMPA-GluR3B antibodies were produced in five mouse strains following immunization with the GluR3B peptide, and then bound neurons, activated AMPA receptors, killed neurons by ‘Excitotoxicity’ and caused brain damage in vivo.
2024年11月22日 · as lead candidates for potent and selective GluR3 inhibitors. The shared molecular mechanisms between depression and AD provide an opportunity for novel treatment approaches that address both conditions simultaneously.
Anti-GluR3 Antibodies | Invitrogen - Thermo Fisher Scientific
Antibodies that detect GluR3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target GluR3 in Human, Mouse, Rat and Non-human primate samples.
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